dc.contributor.author
Gasa Falcón, Ariadna
dc.contributor.author
Odriozola Serrano, Isabel
dc.contributor.author
Oms Oliu, Gemma
dc.contributor.author
Martín Belloso, Olga
dc.date.accessioned
2024-12-05T21:44:22Z
dc.date.available
2024-12-05T21:44:22Z
dc.date.issued
2020-03-30T07:27:08Z
dc.date.issued
2020-03-30T07:27:08Z
dc.date.issued
2020-03-11
dc.identifier
https://doi.org/10.3390/foods9030325
dc.identifier
http://hdl.handle.net/10459.1/68365
dc.identifier.uri
http://hdl.handle.net/10459.1/68365
dc.description.abstract
Acquisition of a healthy lifestyle through diet has driven the food manufacturing industry to produce new food products with high nutritional quality. In this sense, consumption of bioactive compounds has been associated with a decreased risk of suffering chronic diseases. Nonetheless, due to their low solubility in aqueous matrices, high instability in food products during processing and preparation as well as poor bioavailability, the use of such compounds is sometimes limited. Recent advancements in encapsulation and protection of bioactive compounds has opened new possibilities for the development of novel food products. In this direction, the present review is attempting to describe encapsulation achievements, with special attention to nanostructured lipid-based delivery systems, i.e., nanoemulsions, multi-layer emulsions and liposomes. Functionality of bioactive compounds is directly associated with their bioavailability, which in turn is governed by several complex processes, including the passage through the gastrointestinal tract and transport to epithelial cells. Therefore, an overview of recent research on the properties of these nanostructured lipid-based delivery systems with a strong impact on the functionality of bioactive compounds will be also provided. Nanostructured lipid-based delivery systems might be used as a potential option to enhance the solubility, stability, absorption and, ultimately, functionality of bioactive compounds. Several studies have been performed in this line, modifying the composition of the nanostructures, such as the lipid-type or surfactants. Overall, influencing factors and strategies to improve the efficacy of encapsulated bioactive compounds within nanostructures have been successfully identified. This knowledge can be used to design effective targeted nanostructured lipid-based delivery systems for bioactive compounds. However, there is still a lack of information on food interactions, toxicity and long-term consumption of such nanostructures.
dc.description.abstract
This work was funded by the project AGL2015-65975-R (FEDER, MINECO, UE) and project RTI2018-094268-B-C21 (MCIU, AEI; FEDER, UE).
dc.relation
info:eu-repo/grantAgreement/MINECO//AGL2015-65975-R/ES/DISEÑO DE SISTEMAS NANOESTRUCTURADOS PARA PROTEGER Y LIBERAR COMPUESTOS NATURALES CON ACTIVIDAD FUNCIONAL Y TECNOLOGICA/
dc.relation
info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/RTI2018-094268-B-C21/ES/MEJORA DE LAS PROPIEDADES TECNOLOGICAS Y NUTRICIONALES DE ALIMENTOS UTILIZANDO GELES Y EMULSIONES FORMADOS A PARTIR DE CARBOHIDRATOS NO PURIFICADOS OBTENIDOS DE FUENTES ALTERN/
dc.relation
Reproducció del document publicat a: https://doi.org/10.3390/foods9030325
dc.relation
Foods, 2020, vol. 9, núm. 3, article number 325, p. 1-21
dc.rights
cc-by (c) Gasa Falcón, Ariadna et al., 2020
dc.rights
info:eu-repo/semantics/openAccess
dc.rights
https://creativecommons.org/licenses/by/4.0/
dc.subject
Lipid digestibility
dc.subject
Bioaccessibility
dc.subject
Bioactive compounds
dc.title
Nanostructured lipid-based delivery systems as a strategy to increase functionality of bioactive compounds
dc.type
info:eu-repo/semantics/article
dc.type
info:eu-repo/semantics/publishedVersion
