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Título:
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Are Obesity Indices Useful for Detecting Subclinical Atheromatosis in a Middle-Aged Population?
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Autor/a:
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Sánchez Peña, Enric; Sánchez, Marta; Betriu i Bars, M. Àngels; Rius, Ferran; Torres, Gerard; Purroy Garcia, Francisco; Pamplona Gras, Reinald; Ortega, Marta; López Cano, Carolina; Hernández García, Marta; Bueno Díez, Marta; Fernández i Giráldez, Elvira; Salvador, Javier; Lecube Torelló, Albert; ILERVAS project collaborators
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Notas:
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Objective: There is a close relationship between excess adiposity and cardiovascular disease. Although body mass index (BMI) is the most used approach to estimate excess weight, other anthropometric indices have been developed to measure total body and abdominal adiposity. Here, our objective was to assess the usefulness of these anthropometric indices to detect subclinical atheromatous disease.
Methods: A cross-sectional study with 6,809 middle-aged subjects (mean age, 57 [53-63] years) with low to moderate cardiovascular risk from the ILERVAS project. Measures of total body fat (BMI, Clínica Universidad de Navarra - Body Adiposity Estimator [CUN-BAE], and Deurenberg's formula) and central adiposity (waist and neck circumferences, conicity index, waist-to-height ratio, Bonora's equation, the A body adiposity index, and body roundness index) were performed in all participants. Bilateral carotid and femoral ultrasound vascular studies allowed the identification of subjects with plaque. -Results: All measured indices were significantly higher in males with subclinical carotid or femoral plaques (p ≤ 0.021 for all). Also, a positive and significant correlation between all indices and the number of affected territories was found (p ≤ 0.013 for all). From the ROC analysis, all measurements identified patients with asymptomatic atheromatosis but none of them helped make clinical decisions. Regarding females, the results were less conclusive.
Conclusion: Obesity indices are related to subclinical atheromatosis, especially in men, in a large cohort of middle-aged subjects. However, the indices could not detect the presence of arterial plaque, so, when used in isolation, are unlikely to be decisive.
This work was supported by grants from the Diputació de Lleida and Generalitat de Catalunya (2017SGR696 and SLT0021600250) and Menarini Spain S.A. CIBER de Diabetes y Enfermedades Metabólicas Asociadas and CIBER de Enfermedades Respiratorias are initiatives of the Instituto de Salud Carlos III. |
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Materia(s):
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-Obesity indices
-Adipose tissue
-Excess body weight
-Subclinical atheromatosis |
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Derechos:
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cc-by-nc-nd, (c) Sánchez, Enric et al., 2020
http://creativecommons.org/licenses/by-nc-nd/4.0/
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Tipo de documento:
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Artículo
Artículo - Versión publicada |
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Editor:
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Karger Publishers
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Compartir:
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