Vulvar Basal Cell Carcinoma: four case reports with immunohistochemical study

Basal cell carcinoma of the vulva: immunohistochemical analysis of four cases report

dc.contributor.author
García de la Fuente, María Reyes
dc.contributor.author
Santacana Espasa, Maria
dc.contributor.author
Vilardell, Felip
dc.contributor.author
Garí Marsol, Eloi
dc.contributor.author
Casanova i Seuma, Josep M. (Josep Manel)
dc.date.accessioned
2024-12-05T22:40:51Z
dc.date.available
2024-12-05T22:40:51Z
dc.date.issued
2021-10-28T09:43:35Z
dc.date.issued
2021-10-28T09:43:35Z
dc.date.issued
2017-05-01
dc.date.issued
2021-10-28T09:43:35Z
dc.identifier
https://doi.org/10.1177/1203475417712498
dc.identifier
1203-4754
dc.identifier
1615-710X
dc.identifier
http://hdl.handle.net/10459.1/72169
dc.identifier.uri
http://hdl.handle.net/10459.1/72169
dc.description.abstract
Basal cell carcinomas (BCC) are the most frequent tumours in humans and normally appear in photoexposed areas of the skin. It is widely accepted that BCCs originate at follicular stem cells and consequently are very rare in nonhairy areas. Here, we report 4 cases of vulvar BCC, 3 of which were located in a vulvar semimucous area, a nonphotoexposed area, and a nonhairy area. We have determined the CK7 and CK19 profile of all cases; both are markers of simple epithelium with glandular differentiation. Interestingly, all cases were positively stained for CK7 and CK19. Considering that the vulvar region is rich in sebaceous and apocrine units, we hypothesise a glandular origin of BCCs situated in the vulvar region.
dc.format
application/pdf
dc.language
eng
dc.publisher
SAGE Publications
dc.relation
Versió preprint del document publicat a: https://doi.org/10.1177/1203475417712498
dc.relation
Journal of Cutaneous Medicine And Surgery, 2017, vol. 21, núm. 5, p. 457-459
dc.rights
(c) Authors, 2017
dc.rights
info:eu-repo/semantics/openAccess
dc.subject
Apocrine glands
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Basal cell carcinoma
dc.subject
Cytokeratins
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Hair follicle
dc.title
Vulvar Basal Cell Carcinoma: four case reports with immunohistochemical study
dc.title
Basal cell carcinoma of the vulva: immunohistochemical analysis of four cases report
dc.type
info:eu-repo/semantics/article
dc.type
submittedVersion


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