Sistema de Salut de Catalunya
Institut Català de la Salut
[Alfares BA] Department of Radiology, Medical Imaging Center, University Medical Centre Groningen, Groningen, The Netherlands. King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia. [van der Doef HPJ] Division of Paediatric Gastroenterology and Hepatology, Department of Paediatrics, University Medical Centre Groningen, Groningen, The Netherlands. [Wildhaber BE] Swiss Paediatric Liver Centre, Division of Child and Adolescent Surgery, Geneva University Hospitals, Geneve, Switzerland. [Casswall T] Department Clinical Interventions and Technology Clintec, Division for Paediatrics, Karolinska Institute, Stockholm, Sweden. [Nowak G] Department Clinical Interventions and Technology Clintec, Division for Transplantation Surgery, Karolinska Institute, Stockholm, Sweden. [Delle M] Department Clinical Science, Intervention and Technology Clintec, Division for Interventional Radiology, Karolinska Institute, Stockholm, Sweden. [Bernabeu JQ, Hally MM, LK Mauricio] Unitat de Gastroenterologia, Hepatologia, Suport Nutricional i Trasplantaments Hepàtics Pediàtrics, Vall d’Hebron Hospital Universitari, Barcelona, Spain
Vall d'Hebron Barcelona Hospital Campus
2023-08-24T10:04:05Z
2023-08-24T10:04:05Z
2023-07-27
Interventional radiology; Paediatric hepatology; Paediatric transplant surgery
Radiologia intervencionista; Hepatologia pediàtrica; Cirurgia de trasplantament pediàtric
Radiología intervencionista; Hepatología pediátrica; Cirugía de trasplante pediátrico
Introduction Portal vein obstruction (PVO) consists of anastomotic stenosis and thrombosis, which occurs due to a progression of the former. The aim of this large-scale international study is to assess the prevalence, current management practices and efficacy of treatment in patients with PVO. Methods and analysis The Portal vein Obstruction Revascularisation Therapy After Liver transplantation registry will facilitate an international, retrospective, multicentre, observational study, with 25 centres around the world already actively involved. Paediatric patients (aged <18 years) with a diagnosed PVO between 1 January 2001 and 1 January 2021 after liver transplantation will be eligible for inclusion. The primary endpoints are the prevalence of PVO, primary and secondary patency after PVO intervention and current management practices. Secondary endpoints are patient and graft survival, severe complications of PVO and technical success of revascularisation techniques. Ethics and dissemination Medical Ethics Review Board of the University Medical Center Groningen has approved the study (METc 2021/072). The results of this study will be disseminated via peer-reviewed publications and scientific presentations at national and international conferences.
Article
Published version
English
Vena porta; Infants; Fetge - Trasplantació - Complicacions; ANATOMY::Cardiovascular System::Blood Vessels::Veins::Portal System::Portal Vein; ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Therapeutics::Biological Therapy::Cell- and Tissue-Based Therapy::Tissue Transplantation::Liver Transplantation; Other subheadings::Other subheadings::Other subheadings::/adverse effects; NAMED GROUPS::Persons::Age Groups::Child; ANATOMÍA::sistema cardiovascular::vasos sanguíneos::venas::sistema porta::vena porta; TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::terapéutica::terapia biológica::tratamientos basados en células y tejidos::trasplante de tejidos::trasplante de hígado; Otros calificadores::Otros calificadores::Otros calificadores::/efectos adversos; DENOMINACIONES DE GRUPOS::personas::Grupos de Edad::niño
BMJ
BMJ Open;13(7)
http://dx.doi.org/10.1136/bmjopen-2022-066343
Attribution-NonCommercial 4.0 International
http://creativecommons.org/licenses/by-nc/4.0/
Articles científics - HVH [3440]
