dc.contributor
Institut Català de la Salut
dc.contributor
[Torres-Durán M] Pneumology Department, Hospital Álvaro Cunqueiro, NeumoVigo I+i Research Group, IIS Galicia Sur, Vigo, Spain. [López-Campos JL] Instituto de Salud Carlos III, Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Madrid, Spain. Medical and Surgery Unit for Respiratory Diseases, Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío/Universidad de Sevilla, Seville, Spain. [Calle Rubio M] Pneumology Department, Research Institute of Hospital Clínico San Carlos (IdISSC), Department of Medicine, Faculty of Medicine, University Complutense of Madrid, Madrid, Spain. [Montero-Martínez C] Pneumology Department, Hospital Universitario de A Coruña, A Coruña, Spain. [Priegue Carrera A] Nursing Unit, Hospital Álvaro Cunqueiro, Pontevedra, Spain. [Amaro Rodríguez R] Pneumology Department, Hospital Clínic, Barcelona, Spain. [Barrecheguren M] Servei de Pneumologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. [Barrio Guirado MÁ, García-Meseguer P] Vall d’Hebron Hospital Universitari, Barcelona, Spain. [Montoro-Ronsano JB] Servei de Farmàcia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. [Miravitlles M] Servei de Pneumologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain
dc.contributor
Vall d'Hebron Barcelona Hospital Campus
dc.contributor.author
Torres-Duran, María
dc.contributor.author
Montero Martínez, Carmen
dc.contributor.author
Priegue Carrera, Ana
dc.contributor.author
Amaro, Rosanel
dc.contributor.author
Barrecheguren, Miriam
dc.contributor.author
Barrio Guirado, MªAngeles
dc.contributor.author
García-Meseguer, Pilar
dc.contributor.author
López-Campos Bodineau, José Luis
dc.contributor.author
Calle Rubio, Myriam
dc.contributor.author
Montoro-Ronsano, J. Bruno
dc.contributor.author
Miravitlles, Marc
dc.date.accessioned
2025-10-24T08:57:06Z
dc.date.available
2025-10-24T08:57:06Z
dc.date.issued
2023-08-30T11:04:27Z
dc.date.issued
2023-08-30T11:04:27Z
dc.date.issued
2023-08-04
dc.identifier
Torres-Durán M, López-Campos JL, Calle Rubio M, Montero-Martínez C, Priegue Carrera A, Amaro Rodríguez R, et al. Recommendations for the Implementation of the Self-Administration of Alpha-1 Antitrypsin. Int J Chron Obstruct Pulmon Dis. 2023 Aug 4;18:1691–700.
dc.identifier
https://hdl.handle.net/11351/10183
dc.identifier
10.2147/COPD.S410611
dc.identifier
001046690200001
dc.identifier.uri
https://hdl.handle.net/11351/10183
dc.description.abstract
Alpha-1 antitrypsin deficiency; Sugmentation therapy; Self-administration
dc.description.abstract
Deficiència d'alfa-1 antitripsina; Teràpia d'augment; Autoadministració
dc.description.abstract
Deficiencia de alfa-1 antitripsina; Terapia de aumento; Autoadministración
dc.description.abstract
Purpose: Administration of exogenous alpha-1 antitrypsin (AAT) is the only specific therapy for the management of pulmonary morbidity in patients with AAT deficiency. It requires weekly or biweekly intravenous infusions, which may impact patient independence and quality of life. Self-administration of AAT therapy is an alternative to reduce the burden for patients who require AAT therapy. We presented herein experts’ recommendations for the implementation of a program for the self-administration of AAT.
Methods: This project was conducted using a modified nominal group technique and was undertaken in two online meetings involving the participation of 25 experts: specialists in pulmonology (n=17), nurses (n=5) and hospital pharmacists (n=3).
Results: The following issues were discussed, and several recommendations were agreed upon on the following topics: a) patient profile and clinical evaluation, establishing selection criteria that should include clinical as well as social criteria; b) role of health care professionals, suggested roles for specialists in pulmonology, nurses, and hospital pharmacists; c) training by the nurse, including recommendations before initiating the training and the content of the training sessions; and d) logistic issues and follow-up, adherence, and patient support.
Conclusion: We expect this proposal to increase awareness of this therapeutic alternative and facilitate the implementation of self-administration programs, thus contributing to optimizing the patient experience with AAT therapy. Further research on the outcomes of these programs, especially from the patient perspective, will also help to improve their design and implementation.
dc.description.abstract
This project was funded by CSL Behring España.
dc.format
application/pdf
dc.publisher
Dove Medical Press
dc.relation
International Journal of Chronic Obstructive Pulmonary Disease;18
dc.relation
http://dx.doi.org/10.2147/COPD.S410611
dc.rights
Attribution-NonCommercial 4.0 International
dc.rights
http://creativecommons.org/licenses/by-nc/4.0/
dc.rights
info:eu-repo/semantics/openAccess
dc.subject
Pulmons - Malalties - Tractament
dc.subject
Alfa 1-antitripsina - Ús terapèutic
dc.subject
Teràpia intravenosa
dc.subject
CHEMICALS AND DRUGS::Amino Acids, Peptides, and Proteins::Peptides::Serpins::alpha 1-Antitrypsin
dc.subject
Other subheadings::Other subheadings::/therapeutic use
dc.subject
ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Therapeutics::Drug Therapy::Drug Administration Routes::Administration, Intravenous::Infusions, Intravenous
dc.subject
DISEASES::Respiratory Tract Diseases::Lung Diseases
dc.subject
COMPUESTOS QUÍMICOS Y DROGAS::aminoácidos, péptidos y proteínas::péptidos::serpinas::alfa 1-antitripsina
dc.subject
Otros calificadores::Otros calificadores::/uso terapéutico
dc.subject
TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::terapéutica::farmacoterapia::vías de administración de medicamentos::administración intravenosa::infusiones intravenosas
dc.subject
ENFERMEDADES::enfermedades respiratorias::enfermedades pulmonares
dc.title
Recommendations for the Implementation of the Self-Administration of Alpha-1 Antitrypsin
dc.type
info:eu-repo/semantics/article
dc.type
info:eu-repo/semantics/publishedVersion
