Validity of the ADHD module of the Mini International Neuropsychiatric Interview PLUS for screening of adult ADHD in treatment seeking substance use disorder patients: ADHD screening with MINI-Plus

Abstract

Comorbidity; Psychometrics; Substance use disorder

Comorbilitat; Psicometria; Trastorn per consum de substàncies

Comorbilidad; Psicometría; Trastorno por consumo de sustancias

Objective This study aims to assess the validity of the ADHD module of the Mini-International Neuropsychiatric Interview (MINI-Plus) in patients with substance use disorders (SUD), using the Conners’ Adult ADHD Diagnostic Interview for DSM-IV (CAADID) as the external criterion. Method A cross sectional international multi-center study in 10 countries was conducted in treatment seeking SUD patients. A sample of 1263 patients with both MINI-Plus and CAADID was analyzed to determine the psychometric properties of the MINI-Plus. Results According to the CAADID, 179 patients (14.2%) met criteria for adult ADHD, whereas according to the MINI-Plus 227 patients (18.0%) were identified as having adult ADHD. Sensitivity of the MINI-Plus ADHD module was 74%, specificity was 91%, positive predictive value was 60% and negative predictive value was 96%. Kappa was 0.60. Conclusion The MINI-Plus has acceptable criterion validity for the screening of adult ADHD in treatment seeking SUD patients. Scientific significance On the basis of the results, The MINI-Plus may be used for the screening of ADHD in SUD patients.

The IASP study was funded by several institutions in each country. The ICASA Foundation developed the study and coordinated with each institution the regional funding process. The funding sources did not have any influence on the study (research protocol, sampling, issues, analyses, publication). Australia: a strategic grant from Curtin University of Technology (Perth, Western Australia) funded the IAS screening phase. Belgium: the IASP project in this country received private funding. Hungary: No direct funding was received, it was supported by a grant from The European Union and European Social Fund (under agreement to finance the project) no. TÁMOP 4.2.1./B-09/1/KMR-2010-0003. The Netherlands, Amsterdam: no external funding was obtained. The participating institute, Arkin, paid for the costs involved. Norway, Bergen Clinics Foundation: 50% of funding was provided by the Regional Research Council For Addiction in West Norway (Regionalt kompetansesenter for rusmiddelforskning I Helse Vest (KORFOR); the remaining 50% was supported by Bergen Clinics Foundation (Staff and infrastructure). Norway, Fredrikstad: The IASP was funded by the hospital (Sykehuset Østfold HF) not with money, but with 50% of the salary of the participants, then by two sources outside the hospital: The Regional center of Dual Diagnosis and the social – and Health directory. Spain, Barcelona: Financial support was received from Plan Nacional sobre Drogas, Ministerio de Sanidad y Política Social (PND 0080/2011), the Agència de Salut Pública de Barcelona and the Departament de Salut, Government of Catalonia, Spain. Sweden, Stockholm: The study was funded by the Stockholm Center for Dependency Disorders. Switzerland, Berne/Zurich: The IASP in Switzerland was funded by the Swiss Foundation of Alcohol Research (Grant # 209). USA, Syracuse: no funding was obtained. The funding sources did not have influence on: who participated as an author in this study; the research protocol; the sampling of data; the topics chosen for publications; the analyses of the data; the content of the publication.