Sistema de Salut de Catalunya
Institut Català de la Salut
[Dávila Fajardo R] Department of Radiation Oncology, University Medical Center, Utrecht, the Netherlands. Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands. Division Imaging and Oncology, University Medical Center, Utrecht, the Netherlands. [Scarzello G] Veneto Institute of Oncology IOV - IRCCS, Padua, Italy. [Gaze MN] Department of Oncology, University College London Hospitals NHS Foundation Trust, London, United Kingdom. [Boterberg T] Department of Radiation Oncology, Ghent University Hospital, Ghent, Belgium. [Cameron A] Bristol Cancer Institute, University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, United Kingdom. [Fuchs J] Department of Pediatric Surgery and Pediatric Urology, University Childreńs Hospital, Tuebingen, Germany. [Ramos M] Servei d’Oncologia Radioteràpica, Vall d’Hebron Hospital Universitari, Barcelona, Spain
Vall d'Hebron Barcelona Hospital Campus
2024-05-03T11:22:04Z
2024-05-03T11:22:04Z
2024-04-07
Brachytherapy; Rhabdomyosarcoma; Soft tissue sarcoma
Braquiteràpia; Rabdomiosarcoma; Sarcoma de teixit tou
Braquiterapia; Rabdomiosarcoma; Sarcoma de tejido blando
Background and purpose The purpose of this study was to address the lack of published data on the use of brachytherapy in pediatric rhabdomyosarcoma by describing current practice as starting point to develop consensus guidelines. Materials and methods An international expert panel on the treatment of pediatric rhabdomyosarcoma comprising 24 (pediatric) radiation oncologists, brachytherapists and pediatric surgeons met for a Brachytherapy Workshop hosted by the European paediatric Soft tissue Sarcoma Study Group (EpSSG). The panel’s clinical experience, the results of a previously distributed questionnaire, and a review of the literature were presented. Results The survey indicated the most common use of brachytherapy to be in combination with tumor resection, followed by brachytherapy as sole local therapy modality. HDR was increasingly deployed in pediatric practice, especially for genitourinary sites. Brachytherapy planning was mostly by 3D imaging based on CT. Recommendations for patient selection, treatment requirements, implant technique, delineation, dose prescription, dose reporting and clinical management were defined. Conclusions Consensus guidelines for the use of brachytherapy in pediatric rhabdomyosarcoma have been developed through multicenter collaboration establishing the basis for future work. These have been adopted for the open EpSSG overarching study for children and adults with Frontline and Relapsed RhabdoMyoSarcoma (FaR-RMS).
Article
Published version
English
Infants; Tumors de parts toves - Radioteràpia; Enquestes; Sarcoma - Radioteràpia; Braquiteràpia; ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Therapeutics::Radiotherapy::Brachytherapy; DISEASES::Neoplasms::Neoplasms by Histologic Type::Neoplasms, Connective and Soft Tissue::Neoplasms, Muscle Tissue::Myosarcoma::Rhabdomyosarcoma; Other subheadings::Other subheadings::Other subheadings::/radiotherapy; PSYCHIATRY AND PSYCHOLOGY::Behavior and Behavior Mechanisms::Psychology, Social::Group Processes::Consensus; NAMED GROUPS::Persons::Age Groups::Child; TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::terapéutica::radioterapia::braquiterapia; ENFERMEDADES::neoplasias::neoplasias por tipo histológico::neoplasias de tejido conjuntivo y de tejidos blandos::neoplasias de tejido muscular::miosarcoma::rabdomiosarcoma; Otros calificadores::Otros calificadores::Otros calificadores::/radioterapia; PSIQUIATRÍA Y PSICOLOGÍA::conducta y mecanismos de la conducta::psicología social::procesos de grupo::consenso; DENOMINACIONES DE GRUPOS::personas::Grupos de Edad::niño
Elsevier
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology;195
https://doi.org/10.1016/j.radonc.2024.110273
Attribution 4.0 International
http://creativecommons.org/licenses/by/4.0/
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