Sistema de Salut de Catalunya
Institut Català de la Salut
[Vita D] DSS/EMG/FAA-Angola, Vita International Health Agency, London SW8 4EP, UK. Department of Engineering and Technology, Instituto Superior Politécnico de Tecnologias e Ciências (ISPTEC), Luanda, Angola. Instituto Superior Técnico Militar (ISTM), Luanda, Angola. Department of Forensic Science, Geeta University, Panipat, India. [Aznar ML, Martínez-Campreciós J, Molina I] Unitat de Medicina Tropical i Salut Internacional, Servei de Malalties Infeccioses, Vall d’Hebron Hospital Universitari, Barcelona, Spain. PROSICS, Barcelona, Spain. [Kansietoko DCMS] Complexo Hospitalar Cardio Pulmonar, Cardeal Dom Alexandre de Nascimento, Luanda, Angola
Vall d'Hebron Barcelona Hospital Campus
2024-07-01T11:41:52Z
2024-07-01T11:41:52Z
2024-06-12
Food insecurity; Loss to follow-up; Tuberculosis
Inseguretat alimentària; Pèrdua de seguiment; Tuberculosi
Inseguridad alimentaria; Pérdida de seguimiento; Tuberculosis
Background: Tuberculosis (TB) continues to be a serious public health threat that affects the most vulnerable populations. Patients who are lost to follow-up (LTFU) after TB diagnosis still represent one of the biggest challenges to TB control. Method: In this prospective observational study, we aimed to identify and analyse the risk factors associated with LTFU among TB patients who started first-line TB treatment in the Sanatorium Hospital in Luanda. Result: A total of 113 patients with TB (non-multidrug resistant) were included between August 2018 and September 2019. Seventy-six (67.3%) patients were cured, 27 (23.9%) were LTFU, 5 (4.4%) died, 4 (3.5%) were transferred and 1 (0.9%) presented treatment failure. After excluding those who died, were transferred or failed treatment, we observed that severe TB at the time of diagnosis (OR 9.24, 95% CI 2.18-39.04) and food insecurity were significantly associated with LTFU (OR 5.96, 95% CI 1.66-21.41). Conclusions: The findings of our study can contribute to understanding the reasons for the LTFU of patients with TB and can guide policies and facilitate designing measures to allow better adherence and, therefore, greater treatment success.
Article
Published version
English
Tuberculosi - Angola; Tuberculosi - Factors de risc; Tuberculosi - Tractament; GEOGRAPHICALS::Geographic Locations::Africa::Africa South of the Sahara::Africa, Southern::Angola; ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Probability::Risk::Risk Factors; PUBLIC HEALTH::Environmental Health::Health::Environmental Illness::Communicable Diseases::Tuberculosis; Other subheadings::Other subheadings::Other subheadings::/drug therapy; DENOMINACIONES GEOGRÁFICAS::localizaciones geográficas::África::África subsahariana::África del Sur::Angola; TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::técnicas de investigación::métodos epidemiológicos::estadística como asunto::probabilidad::riesgo::factores de riesgo; SALUD PÚBLICA::salud ambiental::salud::enfermedad ambiental::enfermedades transmisibles::tuberculosis; Otros calificadores::Otros calificadores::Otros calificadores::/farmacoterapia
MDPI
Tropical Medicine and Infectious Disease;9(6)
https://doi.org/10.3390/tropicalmed9060131
Attribution 4.0 International
http://creativecommons.org/licenses/by/4.0/
Articles científics - HVH [3440]
