Plain-language commentary: 2-year findings from the FIREFLEYE next study looking at how well aflibercept injected into affected eyes in babies with retinopathy of prematurity works and how safe it is compared with laser treatment

Other authors

Institut Català de la Salut

[Stahl A] Department of Ophthalmology, University Medicine Greifswald, Ferdinand Sauerbruch Straße, Greifswald, Germany. [Nakanishi H] Division of Neonatal Intensive Care Medicine, Department of Advanced Medicine, Research and Development Center for New Medical Frontiers, Kitasato University School of Medicine, Sagamihara, Japan. [Lepore D] Department of Geriatrics and Neuroscience, Catholic University of the Sacred Heart, A. Gemelli Foundation Istituto di Ricovero e Cura a Carattere Scientifico, Rome, Italy. [Wu WC] Department of Ophthalmology, Linkou Chang Gung Memorial Hospital and College of Medicine, Chang Gung University, Taoyuan City, Taiwan. [Azuma N] Department of Developmental and Regenerative Biology, Medical Research Institute, Institute of Science Tokyo, Tokyo, Japan. [Jacas C] Servei de Psiquiatria, Vall d’Hebron Hospital Universitari, Barcelona, Spain

Vall d'Hebron Barcelona Hospital Campus

Publication date

2025-10-17T12:43:45Z

2025-10-17T12:43:45Z

2025-08



Abstract

Infants; Intravitreal aflibercept; Retinopathy of prematurity


Lactants; Aflibercept intravitreal; Retinopatia del prematur


Lactantes; Aflibercept intravítreo; Retinopatía del prematuro

Document Type

Article


Published version

Language

English

Subjects and keywords

Avaluació de resultats (Assistència sanitària); Infants prematurs; Retina - Malalties - Tractament; Injeccions; Retina - Malalties - Cirurgia per làser; Angiogènesi - Inhibidors - Ús terapèutic; ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Diagnosis::Prognosis::Treatment Outcome; DISEASES::Eye Diseases::Retinal Diseases::Retinopathy of Prematurity; Other subheadings::Other subheadings::/therapy; ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Therapeutics::Drug Therapy::Drug Administration Routes::Injections::Injections, Intraocular::Intravitreal Injections; ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Surgical Procedures, Operative::Ablation Techniques::Laser Therapy; CHEMICALS AND DRUGS::Chemical Actions and Uses::Pharmacologic Actions::Physiological Effects of Drugs::Growth Substances::Angiogenesis Modulating Agents::Angiogenesis Inhibitors; TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::diagnóstico::pronóstico::resultado del tratamiento; ENFERMEDADES::oftalmopatías::enfermedades de la retina::retinopatía del prematuro; Otros calificadores::Otros calificadores::/terapia; TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::terapéutica::farmacoterapia::vías de administración de medicamentos::inyecciones::inyecciones intraoculares::inyecciones intravítreas; TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::intervenciones quirúrgicas::técnicas ablativas::tratamiento con láser; COMPUESTOS QUÍMICOS Y DROGAS::acciones y usos químicos::acciones farmacológicas::efectos fisiológicos de los fármacos::sustancias del crecimiento::moduladores de la angiogénesis::inhibidores de la angiogénesis

Publisher

SAGE Publications

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Rights

Attribution-NonCommercial 4.0 International

http://creativecommons.org/licenses/by-nc/4.0/

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