Risk Factors of Mortality from All Asbestos-Related Diseases: A Competing Risk Analysis

Other authors

[Abós-Herràndiz R, Garcia-Allas I, Rosell-Murphy IM, Tarrés J, Krier-Günther I, Martinez-Artés X] Divisió d’Atenció Primària, Institut Català de la Salut (ICS), Barcelona, Spain Spain. [Rodriguez-Blanco T] Institut Universitari d'Investigació en Atenció Primària (IDIAP Jordi Gol), Barcelona, Spain. Universitat Autònoma de Barcelona (UAB), Cerdanyola del Vallès, Spain. [Albertí-Casas C] Institut Català d’Avaluacions Mèdiques (ICAM), Barcelona, Spain. [Orriols R] Unitat de Pneumologia, Hospitals de Girona i Salt, Institut d'Investigació Biomèdica de Girona (IDIBGI), Girona, Spain. Ciber de Enfermedades Respiratorias (CIBERES), Palma de Mallorca, Spain. [Grimau-Malet I] Palliative Care Unit, Parc Taulí Hospital, Barcelona, Spain. [Canela-Soler J] Departament de Salut Pública, Universitat de Barcelona (UB), Barcelona, Spain. Department of Epidemiology and Biostatistics, College of Public Health, University of South Florida, Tampa, USA

IDIAP Jordi Gol

Publication date

2017-11-30T09:14:07Z

2017-11-30T09:14:07Z

2017-06-07



Abstract

Amiant; Mortalitat; Factors de risc


Asbestos; Mortality; Risk factors


Amianto; Mortalidad; Factores de riesgo


Background: The mortality from all malignant and nonmalignant asbestos-related diseases remains unknown. The authors assessed the incidence and risk factors for all asbestos-related deaths. Methods: The sample included 544 patients from an asbestos-exposed community in the area of Barcelona (Spain), between Jan 1, 1970, and Dec 31, 2006. Competing risk regression through a subdistribution hazard analysis was used to estimate risk factors for the outcomes. Results: Asbestos-related deaths were observed in 167 (30.7%) patients and 57.5% of these deaths were caused by some type of mesothelioma. The incidence rate after diagnosis was 3,600 per 100,000 person-years. In 7.5% of patients death was non-asbestos-related, while pleural and peritoneal mesothelioma were identified in 87 (16.0%) and 18 (3.3%) patients, respectively. Conclusions: Age, sex, household exposure, cumulative nonmalignant asbestos-related disease, and single malignant pathology were identified as risk factors for asbestos-related death. These findings suggest the need to develop a preventive approach to the community and to improve the clinical follow-up process of these patients.

Document Type

Article


Published version

Language

English

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Canadian respiratory journal

https://doi.org/10.1155/2017/9015914

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Attribution 4.0 International

https://creativecommons.org/licenses/by/4.0/

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