Sistema de Salut de Catalunya
Institut Català de la Salut
[Diaz M] Nephrology Department, Hospital Universitari Fundació Puigvert. Barcelona, Spain. Universitat Autònoma de Barcelona, Barcelona, Spain. [Agraz I, Soler MJ] Servei de Nefrologia, Hospital Universitari Vall d'Hebron, Barcelona, Spain. Universitat Autònoma de Barcelona, Barcelona, Spain.
Vall d'Hebron Barcelona Hospital Campus
2019-03-22T12:53:47Z
2019-03-22T12:53:47Z
2019-02-01
Anti-phospholipase A2 receptor antibody; Membranous nephropathy; Spontaneous remission
Anticòs del receptor anti-fosfolipasa A2; Nefropatia membranosa; Remissió espontània
Anticuerpo del receptor anti-fosfolipasa A2; Nefropatía membranosa; Remisión espontánea
Membranous nephropathy (MN) is one of the most common causes of nephrotic syndrome in native kidney biopsies from adults. In 2009, antibodies to the M-type receptor of phospholipase A2 (anti-PLA2R) were identified in idiopathic MN patients, both within the kidney and in the circulation. The clinical course of idiopathic MN is variable and ranges from spontaneous remission to end-stage renal disease. Clinical variables such as proteinuria levels, patient sex, age and renal function at diagnosis have been associated with renal MN progression. In this editorial, we update the importance of anti-PLA2R levels as a prognostic marker in idiopathic MN at the diagnosis of the disease
Article
Published version
English
Glomerulonefritis; Fosfolipases - Immunologia; DISEASES::Male Urogenital Diseases::Urologic Diseases::Kidney Diseases::Nephritis::Glomerulonephritis::Glomerulonephritis, Membranous; Other subheadings::Other subheadings::Other subheadings::/immunology; DISEASES::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Disease Attributes::Disease Progression::Remission, Spontaneous; CHEMICALS AND DRUGS::Enzymes and Coenzymes::Enzymes::Hydrolases::Esterases::Carboxylic Ester Hydrolases::Phospholipases::Phospholipases A::Phospholipases A2; ENFERMEDADES::enfermedades urogenitales masculinas::enfermedades urológicas::enfermedades renales::nefritis::glomerulonefritis::glomerulonefritis membranosa; Otros calificadores::Otros calificadores::Otros calificadores::/inmunología; ENFERMEDADES::afecciones patológicas, signos y síntomas::procesos patológicos::atributos de la enfermedad::progresión de la enfermedad::remisión espontánea; COMPUESTOS QUÍMICOS Y DROGAS::enzimas y coenzimas::enzimas::hidrolasas::esterasas::éster carboxílico hidrolasas::fosfolipasas::fosfolipasas A::fosfolipasas A2
Oxford University Press
Clinical Kidney Journal;12(1)
https://academic.oup.com/ckj/article/12/1/33/5114409
Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
Articles científics - HVH [3440]
