Sistema de Salut de Catalunya
Institut Català de la Salut
[Macías A, Saborit N, Molina I] Servei de Malalties Infeccioses, Hospital Universitari Vall d'Hebron, Barcelona, Spain. PROSICS Barcelona, Barcelona, Spain. Universitat Autònoma de Barcelona Barcelona, Spain. [Sánchez-Montalvá A, Salvador F] Servei de Malalties Infeccioses, Hospital Universitari Vall d'Hebron, Barcelona, Spain. PROSICS Barcelona, Barcelona, Spain. Universitat Autònoma de Barcelona Barcelona, Spain. Grupo de Estudio de Infecciones por Micobacterias, Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica, Madrid, Spain. [Villar A ] Servei de Pneumologia, Hospital Universitari Vall d'Hebron, Barcelona, Spain. Universitat Autònoma de Barcelona Barcelona, Spain. [Tórtola T] Servei de Microbiologia, Hospital Universitari Vall d'Hebron, Barcelona, Spain. Universitat Autònoma de Barcelona Barcelona, Spain.
Vall d'Hebron Barcelona Hospital Campus
2019-06-25T06:56:38Z
2019-06-25T06:56:38Z
2019-01
Immigrant population; Pleural tuberculosis; Tuberculosis diagnostic tools
Població immigrant; Tuberculosi pleural; Eines de diagnòstic per la tuberculosi
Población inmigrante; Tuberculosis pleural; Herramientas de diagnóstico para la tuberculosis
BACKGROUND: The confirmatory diagnosis of pleural tuberculosis (pTB) remains challenging. The aim of this study was to describe the clinical and epidemiological characteristics of pTB patients and assess the yield of different diagnostic procedures in a low burden country with a high rate of immigrant population. METHODS: All adult patients with pTB between 2007 and 2014 were studied retrospectively. RESULTS: One hundred and three out of 843 patients with tuberculosis had pTB. Fifty-three (54.1%) were male, and the median age was 45years (range 18-87years). Fifty-two (50.49%) patients were immigrants. A confirmed diagnosis was reached in 16 patients (15.5%) by microbiological studies of pleural effusion. Lung involvement was demonstrated by sputum smear microscopy in 13/49 (26.5%), sputum GeneXpert MTB/RIF test in 13/20 (65%), and sputum culture in 16/37 (43.2%). High-resolution computed tomography (CT) showed lung involvement in 47.7% of the patients. The cure rate was 91.3% at the 1-year follow-up. Three patients died, all of them within the first month after diagnosis. CONCLUSIONS: The detection of lung involvement increased by two-fold when lung CT was used; this correlated with the likelihood of finding a positive microbiological result on sputum sample testing. Pleural microbiological studies had a low diagnostic yield, and sputum could have a complementary role.
Article
Published version
English
Immigrants - Malalties - Diagnòstic; Pleura - Tuberculosi - Diagnòstic; Pleura - Tuberculosi - Epidemiologia; DISEASES::Bacterial Infections and Mycoses::Bacterial Infections::Gram-Positive Bacterial Infections::Actinomycetales Infections::Mycobacterium Infections::Tuberculosis::Tuberculosis, Pleural; Other subheadings::Other subheadings::/diagnosis; Other subheadings::Other subheadings::Other subheadings::/epidemiology; NAMED GROUPS::Persons::Emigrants and Immigrants; ENFERMEDADES::infecciones bacterianas y micosis::infecciones bacterianas::infecciones por bacterias grampositivas::infecciones por Actinomycetales::micobacteriosis::tuberculosis::tuberculosis pleural; Otros calificadores::Otros calificadores::/diagnóstico; Otros calificadores::Otros calificadores::Otros calificadores::/epidemiología; DENOMINACIONES DE GRUPOS::personas::emigrantes e inmigrantes
Elsevier
International Journal of Infectious Diseases;78
https://www.sciencedirect.com/science/article/pii/S120197121834551X?via%3Dihub
Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
Articles científics - HVH [3440]
