Quality of life after transcatheter or surgical aortic valve replacement using the Toronto Aortic Stenosis Quality of Life Questionnaire

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Institut Català de la Salut

[Kennon S] Department of Cardiology, Barts Heart Centre, St Bartholomew’s Hospital, London, UK. [Styra R] Department of Psychiatry, University Health Network, Toronto, Ontario, Canada. [Bonaros N, Stastny L] Department of Cardiac Surgery, Innsbruck Medical University, Innsbruck, Austria. [Romano M] Department of Thoracic and Cardiovascular Surgery, Hopital Prive Jacques Cartier, Massy, France. [Lefèvre T] Institut Jacques Cartier, Massy, France. [Garcia B] Servei de Cardiologia, Vall d'Hebron Hospital Universitari, Barcelona, Spain. CIBER CV, Barcelona, Spain

Vall d'Hebron Barcelona Hospital Campus

Publication date

2022-05-13T06:25:21Z

2022-05-13T06:25:21Z

2021-12



Abstract

Malalties aòrtiques; Pròtesi de vàlvula cardíaca; Qualitat de l'assistència sanitària


Enfermedades aórticas; Prótesis de válvula cardíaca; Calidad de la asistencia sanitaria


Aortic diseases; Heart valve prosthesis; Quality of healthcare


Background The Toronto Aortic Stenosis Quality of Life Questionnaire (TASQ) is a validated instrument for assessing quality of life (QoL) in patients with severe aortic stenosis (AS). In this study, we evaluated health status outcomes, based on the TASQ, in patients with severe AS undergoing transcatheter aortic valve replacement (TAVR) or surgical aortic valve replacement (SAVR). Methods The TASQ registry was a prospective observational registry. Patients with severe AS from nine centres in Europe and one in Canada underwent either SAVR or transfemoral TAVR. Patients completed the TASQ, Kansas City Cardiomyopathy Questionnaire and Short Form-12 V.2 prior to the intervention, predischarge, and at 30-day and 3-month follow-ups. Primary end point was the TASQ score. Results In both the TAVR (n=137) and SAVR (n=137) cohorts, significant increases were observed in all three scores. The overall TASQ score improved as did all but one of the individual domains at 3 months after the intervention (p<0.001). TASQ health expectations were the only domain which worsened (p<0.001). Across TASQ subscores, significant changes were evident from the time of discharge in the TAVR and 30-day follow-up in the SAVR cohort. In a categorical analysis of the TASQ, 39.7% of the TAVR group and 35.0% of the SAVR group had a substantially improved health status at 3 months compared with baseline. Conclusions The TASQ captured changes in QoL among patients with severe AS who were treated with TAVR or SAVR. QoL improved substantially after either intervention, as indicated by changes in the TASQ overall score at 3 months.


This work was supported by a research grant provided by Edwards Lifesciences (Nyon, Switzerland) to the Institute for Pharmacology and Preventive Medicine (Cloppenburg, Germany).

Document Type

Article


Published version

Language

English

Publisher

BMJ

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Open Heart;8(2)

http://dx.doi.org/10.1136/openhrt-2021-001821

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Attribution-NonCommercial 4.0 International

http://creativecommons.org/licenses/by-nc/4.0/

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