dc.contributor
Institut Català de la Salut
dc.contributor
[Psychogios MN] Department of Neuroradiology, Clinic for Radiology & Nuclear Medicine, University Hospital Basel, Basel, Switzerland. [Sporns PB] Department of Neuroradiology, Clinic for Radiology & Nuclear Medicine, University Hospital Basel, Basel, Switzerland. Department of Diagnostic and Interventional Neuroradiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. [Ospel J] Department of Neuroradiology, Clinic for Radiology & Nuclear Medicine, University Hospital Basel, Basel, Switzerland. Department of Clinical Neurosciences, Radiology and Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, Canada. [Katsanos AH] Department of Medicine (Neurology), McMaster University/Population Health Research Institute, Hamilton, Canada. Second Department of Neurology, National and Kapodistrian University of Athens, Athens, Greece. [Kabiri R, Flottmann FA] Department of Diagnostic and Interventional Neuroradiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. [Ribo M, Ruiz MR] Servei de Neurologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain
dc.contributor
Vall d'Hebron Barcelona Hospital Campus
dc.contributor.author
Psychogios, Marios-Nikos
dc.contributor.author
Sporns, Peter Bernhard
dc.contributor.author
Ospel, Johanna M.
dc.contributor.author
Katsanos, Aristeidis H.
dc.contributor.author
Kabiri, Reza
dc.contributor.author
Flottmann, Fabian
dc.contributor.author
Ribó Jacobi, Marc
dc.contributor.author
Requena Ruiz, Manuel
dc.date.accessioned
2025-10-24T10:24:48Z
dc.date.available
2025-10-24T10:24:48Z
dc.date.issued
2022-07-18T10:26:16Z
dc.date.issued
2022-07-18T10:26:16Z
dc.identifier
Psychogios MN, Sporns PB, Ospel J, Katsanos AH, Kabiri R, Flottmann FA, et al. Automated Perfusion Calculations vs. Visual Scoring of Collaterals and CBV-ASPECTS : Has the Machine Surpassed the Eye? Clin Neuroradiol. 2021 Jun;31:499–506.
dc.identifier
https://hdl.handle.net/11351/7781
dc.identifier
10.1007/s00062-020-00974-3
dc.identifier
000591102300002
dc.identifier.uri
https://hdl.handle.net/11351/7781
dc.description.abstract
Acute ischemic stroke; Automated evaluation; Perfusion imaging
dc.description.abstract
Accidente cerebrovascular isquémico agudo; Evaluación automatizada; Imágenes de perfusión
dc.description.abstract
Accident cerebrovascular isquèmic agut; Avaluació automatitzada; Imatge de perfusió
dc.description.abstract
Purpose
Use of automated perfusion software has gained importance for imaging of stroke patients for mechanical thrombectomy (MT). We aim to compare four perfusion software packages: 1) with respect to their association with 3‑month functional outcome after successful reperfusion with MT in comparison to visual Cerebral Blood Volume - Alberta Stroke Program Early CT Score (CBV-ASPECTS) and collateral scoring and 2) with respect to their agreement in estimation of core and penumbra volume.
Methods
This retrospective, multicenter cohort study (2015–2019) analyzed data from 8 centers. We included patients who were functionally independent before and underwent successful MT of the middle cerebral artery. Primary outcome measurements were the relationship of core and penumbra volume calculated by each software, qualitative assessment of collaterals and CBV-APECTS with 3‑month functional outcome and disability (modified Rankin scale >2). Quantitative differences between perfusion software measurements were also assessed.
Results
A total of 215 patients (57% women, median age 77 years) from 8 centers fulfilled the inclusion criteria. Multivariable analyses showed a significant association of RAPID core (common odds ratio, cOR 1.02; p = 0.015), CBV-ASPECTS (cOR 0.78; p = 0.007) and collaterals (cOR 0.78; p = 0.001) with 3‑month functional outcome (shift analysis), while RAPID core (OR 1.02; p = 0.018), CBV-ASPECTS (OR 0.77; p = 0.024), collaterals (OR 0.78; p = 0.007) and OLEA core (OR 1.02; p = 0.029) were significantly associated with 3‑month functional disability. Mean differences on core estimates between VEOcore and RAPID were 13.4 ml, between syngo.via and RAPID 30.0 ml and between OLEA and RAPID −3.2 ml.
Conclusion
Collateral scoring, CBV-ASPECTS and RAPID were independently associated with functional outcome at 90 days. Core and Penumbra estimates using automated software packages varied significantly and should therefore be used with caution.
dc.description.abstract
Open access funding provided by University of Basel
dc.format
application/pdf
dc.relation
Clinical Neuroradiology;31
dc.relation
https://doi.org/10.1007/s00062-020-00974-3
dc.rights
Attribution 4.0 International
dc.rights
http://creativecommons.org/licenses/by/4.0/
dc.rights
info:eu-repo/semantics/openAccess
dc.subject
Isquèmia cerebral - Imatgeria
dc.subject
Vasos sanguinis - Cirurgia
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Avaluació de resultats (Assistència sanitària)
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DISEASES::Nervous System Diseases::Central Nervous System Diseases::Brain Diseases::Cerebrovascular Disorders::Brain Ischemia
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Other subheadings::Other subheadings::Other subheadings::/diagnostic imaging
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ENFERMEDADES::enfermedades del sistema nervioso::enfermedades del sistema nervioso central::enfermedades cerebrales::trastornos cerebrovasculares::isquemia cerebral
dc.subject
Otros calificadores::Otros calificadores::Otros calificadores::/diagnóstico por imagen
dc.title
Automated Perfusion Calculations vs. Visual Scoring of Collaterals and CBV-ASPECTS: Has the Machine Surpassed the Eye?
dc.type
info:eu-repo/semantics/article
dc.type
info:eu-repo/semantics/publishedVersion
