dc.contributor
[Rey-Reñones C] Research Support Unit-Camp de Tarragona, Catalan Institute of Health (ICS), Tarragona, Spain. IDIAP Jordi Gol, Catalan Institute of Health (ICS), Barcelona, Spain. School of Medicine and Health Sciences, Universitat Rovira i Virgili, Reus, Spain. [Baena-Díez JM] IDIAP Jordi Gol, Catalan Institute of Health (ICS), Barcelona, Spain. La Marina Primary Care Center, Catalan Institute of Health (ICS), Barcelona, Spain. [Aguilar-Palacio I] Research Group in Health Services of Aragon, (GRISSA) IIS Aragón, University of Zaragoza, Zaragoza, Spain. [Miquel C] Department of Medicine, University of Barcelona, Barcelona, Spain. [Grau M] Serra Húnter Fellow, Department of Medicine, University of Barcelona, Barcelona, Spain. Biomedical Research Consortium in Epidemiology and Public Health (CIBERESP), Barcelona, Spain. IMIM-Institut Hospital del Mar d’Investigacions Mèdiques, Barcelona, Spain
dc.contributor
Departament de Salut
dc.contributor.author
Baena-Diez, José Miguel
dc.contributor.author
Aguilar-Palacio, Isabel
dc.contributor.author
Miquel, Cristina
dc.contributor.author
Grau, Maria
dc.contributor.author
Rey-Reñones, Cristina
dc.date.accessioned
2025-10-24T10:58:53Z
dc.date.available
2025-10-24T10:58:53Z
dc.date.issued
2022-09-20T12:34:59Z
dc.date.issued
2022-09-20T12:34:59Z
dc.date.issued
2021-10-09
dc.identifier
Rey-Reñones C, Baena-Díez JM, Aguilar-Palacio I, Miquel C, Grau M. Type 2 Diabetes Mellitus and Cancer: Epidemiology, Physiopathology and Prevention. Biomedicines. 2021 Oct 9;9(10):1429.
dc.identifier
https://hdl.handle.net/11351/8230
dc.identifier
10.3390/biomedicines9101429
dc.identifier.uri
https://hdl.handle.net/11351/8230
dc.description.abstract
Type-2 diabetes mellitus; Epidemiology; Cancer
dc.description.abstract
Diabetes tipo 2; Epidemiología; Cáncer
dc.description.abstract
Diabetis tipus 2; Epidemiologia; Càncer
dc.description.abstract
Individuals with type 2 diabetes mellitus are at greater risk of developing cancer and of dying from it. Both diseases are age-related, contributing to the impact of population aging on the long-term sustainability of health care systems in European Union countries. The purpose of this narrative review was to describe, from epidemiological, pathophysiological and preventive perspectives, the links between type 2 diabetes mellitus and the most prevalent cancers in these patients. Multiple metabolic abnormalities that may occur in type 2 diabetes mellitus, particularly obesity, could explain the increased cancer risk. In addition, the effectiveness of drugs commonly used to treat type 2 diabetes mellitus (e.g., metformin and thiazolidinediones) has been broadly evaluated in cancer prevention. Thus, a better understanding of the links between type 2 diabetes mellitus and cancer will help to identify the contributing factors and the pathophysiological pathways and to design personalized preventive strategies. The final goal is to facilitate healthy aging and the prevention of cancer and other diseases related with type 2 diabetes mellitus, which are among the main sources of disability and death in the European Union and worldwide.
dc.format
application/pdf
dc.relation
Biomedicines;9(10)
dc.relation
https://doi.org/10.3390/biomedicines9101429
dc.rights
Attribution 4.0 International
dc.rights
https://creativecommons.org/licenses/by/4.0/
dc.rights
info:eu-repo/semantics/openAccess
dc.subject
Diabetis no-insulinodependent
dc.subject
Oncologia - Malalties - Prevenció
dc.subject
DISEASES::Endocrine System Diseases::Diabetes Mellitus::Diabetes Mellitus, Type 2
dc.subject
DISEASES::Neoplasms
dc.subject
Other subheadings::Other subheadings::Other subheadings::/complications
dc.subject
ENFERMEDADES::enfermedades del sistema endocrino::diabetes mellitus::diabetes mellitus tipo II
dc.subject
ENFERMEDADES::neoplasias
dc.subject
Otros calificadores::Otros calificadores::Otros calificadores::/complicaciones
dc.title
Type 2 Diabetes Mellitus and Cancer: Epidemiology, Physiopathology and Prevention
dc.type
info:eu-repo/semantics/article
dc.type
info:eu-repo/semantics/publishedVersion
