Sistema de Salut de Catalunya
Institut Català de la Salut
[Denyer H] Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, UK. [Ramos-Quiroga JA] Servei de Psiquiatria, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Grup de Recerca de Psiquiatria, Salut Mental i Addiccions, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Biomedical Network Research Centre on Mental Health (CIBER SAM), Barcelona, Catalonia, Spain. Departament de Psiquiatria i Medicina Forense, Universitat Autònoma de Barcelona, Bellaterra, Spain. [Folarin A] Department of Biostatistics and Health Informatics, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, UK. Institute of Health Informatics, University College London, London, UK. NIHR Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and King’s College London, London, UK. Health Data Research UK London, University College London, London, UK. NIHR Biomedical Research Centre at University College London Hospitals NHS Foundation Trust, London, UK. [Ramos C] Grup de Recerca de Psiquiatria, Salut Mental i Addiccions, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. [Nemeth P] Empatica Srl, Milan, Italy. [Bilbow A] The National Attention Defcit Disorder Information and Support Service, ADDISS, Edgware, Middlesex, UK
Vall d'Hebron Barcelona Hospital Campus
2023-01-26T10:30:52Z
2023-01-26T10:30:52Z
2022-12-20
Attention deficit hyperactivity disorder; Digital phenotyping; Remote monitoring
Trastorno por déficit de atención con hiperactividad; Fenotipado digital; Monitoreo remoto
Transtorn per dèficit d'atenció amb hiperactivitat; Fenotipat digital; Monitorització remota
Background Emerging evidence points at substantial comorbidity between adult attention deficit hyperactivity disorder (ADHD) and cardiometabolic diseases, but our understanding of the comorbidity and how to manage cardiometabolic disease in adults with ADHD is limited. The ADHD Remote Technology study of cardiometabolic risk factors and medication adherence (ART-CARMA) project uses remote measurement technology to obtain real-world data from daily life to assess the extent to which ADHD medication treatment and physical activity, individually and jointly, may influence cardiometabolic risks in adults with ADHD. Our second main aim is to obtain valuable real-world data on adherence to pharmacological treatment and its predictors and correlates during daily life from adults with ADHD. Methods ART-CARMA is a multi-site prospective cohort study within the EU-funded collaboration ‘TIMESPAN’ (Management of chronic cardiometabolic disease and treatment discontinuity in adult ADHD patients) that will recruit 300 adults from adult ADHD waiting lists. The participants will be monitored remotely over a period of 12 months that starts from pre-treatment initiation. Passive monitoring, which involves the participants wearing a wrist-worn device (EmbracePlus) and downloading the RADAR-base Passive App and the Empatica Care App on their smartphone, provides ongoing data collection on a wide range of variables, such as physical activity, sleep, pulse rate (PR) and pulse rate variability (PRV), systolic peaks, electrodermal activity (EDA), oxygen saturation (SpO2), peripheral temperature, smartphone usage including social connectivity, and the environment (e.g. ambient noise, light levels, relative location). By combining data across these variables measured, processes such as physical activity, sleep, autonomic arousal, and indicators of cardiovascular health can be captured. Active remote monitoring involves the participant completing tasks using a smartphone app (such as completing clinical questionnaires or speech tasks), measuring their blood pressure and weight, or using a PC/laptop (cognitive tasks). The ART system is built on the RADAR-base mobile-health platform. Discussion The long-term goal is to use these data to improve the management of cardiometabolic disease in adults with ADHD, and to improve ADHD medication treatment adherence and the personalisation of treatment.
The ART-CARMA study has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 965381. This communication reflects the views of the authors, and the European Commission is not responsible for any use that may be made of the information it contains. HD is supported by the UK Medical Research Council (MR/N013700/1) and King’s College London member of the MRC Doctoral Training Partnership in Biomedical Sciences.
Article
Published version
English
Trastorn per dèficit d'atenció amb hiperactivitat - Tractament; Sistema cardiovascular - Malalties; Síndrome metabòlica; Pacients - Cooperació; PSYCHIATRY AND PSYCHOLOGY::Mental Disorders::Neurodevelopmental Disorders::Attention Deficit and Disruptive Behavior Disorders::Attention Deficit Disorder with Hyperactivity; Other subheadings::Other subheadings::Other subheadings::/drug therapy; DISEASES::Nutritional and Metabolic Diseases::Metabolic Diseases::Glucose Metabolism Disorders::Hyperinsulinism::Insulin Resistance::Metabolic Syndrome; DISEASES::Cardiovascular Diseases; PSYCHIATRY AND PSYCHOLOGY::Behavior and Behavior Mechanisms::Attitude::Attitude to Health::Treatment Adherence and Compliance::Patient Acceptance of Health Care::Patient Compliance::Medication Adherence; PSIQUIATRÍA Y PSICOLOGÍA::trastornos mentales::trastornos del desarrollo neurológico::trastornos conductuales disruptivos y déficit de atención::trastornos de déficit de atención con hiperactividad; Otros calificadores::Otros calificadores::Otros calificadores::/farmacoterapia; ENFERMEDADES::enfermedades nutricionales y metabólicas::enfermedades metabólicas::trastornos del metabolismo de la glucosa::hiperinsulinismo::resistencia a la insulina::síndrome metabólico; ENFERMEDADES::enfermedades cardiovasculares; PSIQUIATRÍA Y PSICOLOGÍA::conducta y mecanismos de la conducta::actitud::actitud ante la salud::cumplimiento y adherencia al tratamiento::aceptación de la asistencia sanitaria por parte del paciente::cumplimiento del paciente::adhesión a la medicación
BMC
BMC Psychiatry;22
https://doi.org/10.1186/s12888-022-04429-6
info:eu-repo/grantAgreement/EC/H2020/965381
Attribution 4.0 International
http://creativecommons.org/licenses/by/4.0/
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