Other authors

Institut Català de la Salut

[Valero C] Manchester Fungal Infection Group, Division of Evolution, Infection, and Genomics, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK. [Martín-Gómez MT] Servei de Microbiologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. [Buitrago MJ] Mycology Reference Laboratory, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Majadahonda, Madrid, Spain. CIBERINFEC, ISCIII-CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Majadahonda, Madrid, Spain

Vall d'Hebron Barcelona Hospital Campus

Publication date

2023-03-01T11:29:00Z

2023-03-01T11:29:00Z

2022-12-30



Abstract

Endemic mycoses; Molecular diagnosis


Micosis endémicas; Diagnóstico molecular


Micosis endèmiques; Diagnòstic molecular


Diagnosis of endemic mycoses is still challenging. The moderated availability of reliable diagnostic methods, the lack of clinical suspicion out of endemic areas and the limitations of conventional techniques result in a late diagnosis that, in turn, delays the implementation of the correct antifungal therapy. In recent years, molecular methods have emerged as promising tools for the rapid diagnosis of endemic mycoses. However, the absence of a consensus among laboratories and the reduced availability of commercial tests compromises the diagnostic effectiveness of these methods. In this review, we summarize the advantages and limitations of molecular methods for the diagnosis of endemic mycoses.


This research was funded by research project PI21CIII/00007 from Spanish Fondo de Investigaciones Sanitarias of the Instituto de Salud Carlos III.

Document Type

Article


Published version

Language

English

Publisher

MDPI

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Journal of Fungi;9(1)

https://doi.org/10.3390/jof9010059

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Rights

Attribution 4.0 International

http://creativecommons.org/licenses/by/4.0/

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