Sistema de Salut de Catalunya
Institut Català de la Salut
[Ruano-Ravina A] Department of Preventive Medicine and Public Health, University of Santiago de Compostela, Santiago de Compostela, Spain. Consortium for Biomedical Research in Epidemiology & Public Health (CIBER en Epidemiología and Salud Pública/CIBERESP), Madrid, Spain. Health Research Institute of Santiago de Compostela (Instituto de Investigación Sanitaria de Santiago de Compostela - IDIS), Santiago de Compostela, Spain. [Provencio M, Calvo de Juan V] Department of Oncology, Puerta de Hierro University Hospital, Majadahonda, Madrid, Spain. [Carcereny E, Estival A] Medical Oncology Department, Catalan Institute of Oncology, Badalona- Germans Trias i Pujol Hospital B-ARGO group, Barcelona, Spain. [Rodríguez-Abreu D, Benítez G] Hospital Insular de Gran Canaria, Las Palmas de Gran Canaria, Spain. [López Castro R, Belver M] Servicio de Oncología, Sección de oncología médica, Hospital Clínico Universitario de Valladolid, Valladolid, Spain. [Guirado Risueño M, Guirao-Rubio C] Hospital de Elche, Elche, Spain.[ Blasco A] Hospital General de Valencia, Valencia, Spain. [Massutí B] Hospital Universitario General de Alicante, Alicante, Spain. [Ortega Granados AL] Servicio de Oncología Médica. Complejo Hospitalario de Jaén, Jaén, Spain. [Cobo M] Unidad de Gestión Clínica Intercentros de Oncología Médica, Hospitales Universitarios Regional y Virgen de la Victoria, IBIMA, Málaga, Spain.[ Mosquera-Martínez J] Hospital Universitario de A Coruña, A Coruña, Spain. [Aguado C] Department of Oncology, Clínico San Carlos Hospital, Madrid, Spain. [Bosch-Barrera J] Girona Biomedical Research Institute (IDIBGI), Girona, Spain. Department of Medical Sciences, Medical School, University of Girona, Girona, Spain. Medical Oncology, Catalan Institute of Oncology, Hospital Universitari de Girona Doctor Josep Trueta, Institut Català de la Salut (ICS), Girona, Spain. [Sanchez Gastaldo A] Department of Oncology, Hospital Virgen del Rocío, Seville, Spain. [Del Barco Morillo E] Department of Oncology, Hospital de Salamanca, Salamanca, Spain. [Juan O] Servicio Oncología Médica, Hospital Universitari i Politécnic La Fe, Valencia, Spain. [Dómine M] Hospital Jiménez Díaz, Madrid, Spain. [Trigo J] Servicio de Oncología Médica y Unidad de Fases I, Hospital Universitario Virgen de la Victoria, Málaga, Spain. [Pereiro Corbacho D] Hospital Universitario Álvaro Cunqueiro, Vigo, Spain. [Oramas J] Hospital Universitario de Canarias, Santa Cruz Tenerife, Spain
Hospital Universitari de Girona Dr Josep Trueta
2023-03-10T08:49:35Z
2023-03-10T08:49:35Z
2021-10
Càncer de pulmó; Fumar; Diferències entre sexes
Cancer de pulmón; Fumar; Diferencias entre sexos
Lung neoplasms; Smoking; Sex Factors
Background: Lung cancer causes approximately 25% of all cancer deaths. Despite its relevance, few studies have analyzed differences by sex at the time of diagnosis in terms of symptoms, stage, age or smoking status. We aim to assess if there are differences between men and women on these characteristics at diagnosis. Methods: We analyzed the Thoracic Tumour Registry (TTR), sponsored by the Spanish Lung Cancer Group using a case-series design. This is a nationwide registry of lung cancer cases which started recruitment in 2016. For each case included, clinicians fulfilled an electronic record registering demographic data, symptoms, exposure to lung cancer risk factors, and treatment received in detail. We compared men and women using descriptive statistics. Results: A total of 13,590 participants took part in this study, 25.6% women. Women were 4 years younger than men (64 vs. 69), and men had smoked more frequently. Adenocarcinoma was the most frequent histological type in both sexes. Stage IV at diagnosis was 50.8% in women compared to 43.6% in men. Weight loss/anorexia/asthenia was the most frequent symptom in both sexes and there were no differences in the number of symptoms at diagnosis. There were no relevant differences in the frequency or number of symptoms by sex when non-small cell lung cancer (NSCLC) and small-cell lung cancer (SCLC) were analyzed separately. Smoking status did not appear to cause different lung cancer presentation in men compared to women. Conclusions: There seems to be no differences in lung cancer characteristics by sex at the time at diagnosis on stage, specific symptoms or number of symptoms.
This research received funding from the Spanish Lung Cancer Group
Article
Published version
English
Pulmons - Càncer; Diferències entre sexes; Fumadors; DISEASES::Neoplasms::Neoplasms by Site::Thoracic Neoplasms::Respiratory Tract Neoplasms::Lung Neoplasms; Other subheadings::Other subheadings::/diagnosis; PSYCHIATRY AND PSYCHOLOGY::Behavior and Behavior Mechanisms::Behavior::Smoking; HEALTH CARE::Health Care Quality, Access, and Evaluation::Quality of Health Care::Epidemiologic Factors::Sex Factors; ENFERMEDADES::enfermedades respiratorias::enfermedades respiratorias::neoplasias del tracto respiratorio::neoplasias pulmonares; Otros calificadores::Otros calificadores::/diagnóstico; PSIQUIATRÍA Y PSICOLOGÍA::conducta y mecanismos de la conducta::conducta::fumar; ATENCIÓN DE SALUD::calidad, acceso y evaluación de la atención sanitaria::calidad de la atención sanitaria::factores epidemiológicos::factores sexuales
AME Publishing
Translational Lung Cancer Research;10(10)
https://dx.doi.org/10.21037/tlcr-21-559
Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
