Abnormal Maternal Body Mass Index and Customized Fetal Weight Charts: Improving the Identification of Small for Gestational Age Fetuses and Newborns

Other authors

Institut Català de la Salut

[González González NL, Tascón L] Department of Obstetrics and Gynecology, University of La Laguna, Hospital Universitario de Canarias, Tenerife, Spain. [González Dávila E] Department of Mathematics, Statistics and Operations Research, IMAULL, University of La Laguna, Tenerife, Spain. [González Martín A] Department of Obstetrics and Gynecology, Hospital Universitario Ntra Sra de Candenlaria, Tenerife, Spain. [Armas M] Department of Pediatrics, Evangelisches Krakenhaus König Elisabeth Herzberge, Berlin, Germany. [Farras A, Higueras T, Mendoza M, Carreras E, Goya M] Grup de Recerca en Medicina Materna i Fetal, Àrea d’Obstetrícia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Universitat Autònoma de Barcelona, Bellaterra, Spain

Vall d'Hebron Barcelona Hospital Campus

Publication date

2023-03-16T07:23:31Z

2023-03-16T07:23:31Z

2023-01-22



Abstract

Maternal body mass index; Newborn weight; Obesity


Índice de masa corporal materno; Peso del neonato; Obesidad


Índex de massa corporal matern; Pes del nounat; Obesitat


Background: Obesity and thinness are serious diseases, but cases with abnormal maternal weight have not been excluded from the calculations in the construction of customized fetal growth curves (CCs). Method: To determine if the new CCs, built excluding mothers with an abnormal weight, are better than standard CCs at identifying SGA. A total of 16,122 neonates were identified as SGA, LGA, or AGA, using the two models. Logistic regression and analysis of covariance were used to calculate the OR and CI for adverse outcomes by group. Gestational age was considered as a covariable. Results: The SGA rates by the new CCs and by the standard CCs were 11.8% and 9.7%, respectively. The SGA rate only by the new CCs was 18% and the SGA rate only by the standard CCs was 0.01%. Compared to AGA by both models, SGA by the new CCs had increased rates of cesarean section, (OR 1.53 (95% CI 1.19, 1.96)), prematurity (OR 2.84 (95% CI 2.09, 3.85)), NICU admission (OR 5.41 (95% CI 3.47, 8.43), and adverse outcomes (OR 1.76 (95% CI 1.06, 2.60). The strength of these associations decreased with gestational age. Conclusion: The use of the new CCs allowed for a more accurate identification of SGA at risk of adverse perinatal outcomes as compared to the standard CCs.

Document Type

Article


Published version

Language

English

Publisher

MDPI

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Attribution 4.0 International

http://creativecommons.org/licenses/by/4.0/

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