dc.contributor.author
Guillem Martí, Jordi
dc.contributor.author
Cinca, Núria
dc.contributor.author
Punset Fuste, Miquel
dc.contributor.author
García Cano, Irene
dc.contributor.author
Gil Mur, Francisco Javier
dc.contributor.author
Guilemany, José Maria
dc.contributor.author
Dosta, Sergi
dc.date.accessioned
2025-05-20T00:04:03Z
dc.date.available
2025-05-20T00:04:03Z
dc.date.issued
2019-04-24
dc.identifier.citation
Guillem-Martí, Jordi; Cinca, Núria; Punset, Miquel; García Cano, Irene; Gil Mur, Francesc Xavier; Guilemany, José Maria; Dosta, Sergi. «Porous titanium-hydroxyapatite composite coating obtained on titanium by cold gas spray with high bond strength for biomedical applications». Colloids and Surfaces B: Biointerfaces, 2019, vol. 180, p. 245-253. https://doi.org/10.1016/j.colsurfb.2019.04.048
dc.identifier.issn
0927-7765
dc.identifier.uri
http://hdl.handle.net/20.500.12328/1051
dc.description
This work was supported by the Spanish Government through project MAT2015-67183- R, cofounded by the EU through the European Regional Development Funds. The authors acknowledge also the Generalitat de Catalunya for funding the project 2017SGR-1165 and for the ICREA Award of M-P Ginebra.
dc.description.abstract
The lack of bioactivity of titanium (Ti) is one of the main drawbacks for its application in biomedical implants since it can considerable reduce its osseointegration capacities. One strategy to overcome this limitation is the coating of Ti with hydroxyapatite (HA), which presents similar chemical composition than bone. Nonetheless, most of the strategies currently used generate a non-stable coating and may produce the formation of amorphous phases when high temperatures are used. Herein, we proposed to generate a Ti-HA composite coating on Ti surface to improve the stability of the bioactive coating. The coating was produced by cold gas spraying, which uses relatively low temperatures, and compared to a Ti coating. The coating was thoroughly characterized in terms of morphology, roughness, porosity and phase composition. In addition, the coating was mechanically characterized using a tensile loading machine. Finally, biological response was evaluated after seeding SaOS-2 osteoblasts and measuring cell adhesion, proliferation and differentiation. The novel Ti-HA coating presented high porosity and high adhesion and bond strengths. No change in HA phases was observed after coating formation. Moreover, osteoblast-like cells adhered, proliferated and differentiated on Ti-HA coated surfaces suggesting that the novel coating might be a good candidate for biomedical applications.
dc.relation.ispartof
Colloids and Surfaces B: Biointerfaces
dc.relation.ispartofseries
180;
dc.rights
http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.rights
Attribution-NonCommercial-NoDerivatives 4.0 International
dc.rights.uri
http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subject
Materials biomèdics
dc.subject
Biomedical materials
dc.subject
Materiales biomédicos
dc.subject
Hydroxyapatite coating
dc.title
Porous titanium-hydroxyapatite composite coating obtained on titanium by cold gas spray with high bond strength for biomedical applications
dc.type
info:eu-repo/semantics/article
dc.description.version
info:eu-repo/semantics/acceptedVersion
dc.relation.projectID
info:eu-repo/grantAgreement/ES/1PE/MAT2015-67183-R
dc.identifier.doi
https://doi.org/10.1016/j.colsurfb.2019.04.048
dc.rights.accessLevel
info:eu-repo/semantics/openAccess
