Ethical challenges of germline genetic enhancement

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To access the full text documents, please follow this link: http://hdl.handle.net/20.500.12328/1337

dc.contributor.author	Macpherson Mayol, Ignacio
dc.contributor.author	Roqué Sánchez, María Victoria
dc.contributor.author	Segarra Taus, Ignacio
dc.date	2019-11-19T10:56:06Z
dc.date	2019-11-19T10:56:06Z
dc.date	2019-09-03
dc.identifier	Macpherson Mayol, Ignacio; Roqué Sánchez, María Victoria; Segarra, Ignacio. «Ethical challenges of germline genetic enhancement». Frontiers in Genetics, 2019, vol. 10, art. 767. Disponible en: <https://www.frontiersin.org/articles/10.3389/fgene.2019.00767/full>. Fecha de acceso: 19 nov. 2019. DOI: 10.3389/fgene.2019.00767
dc.identifier	1664-8021
dc.identifier	https://doi.org/10.3389/fgene.2019.00767
dc.identifier.uri	http://hdl.handle.net/20.500.12328/1337
dc.description	This article was submitted to ELSI in Science and Genetics, a section of the journal Frontiers in Genetics
dc.description	The new reproductive technologies have opened the door to different processes of germline genetic enhancement by which the characteristics of an individual according to the interests of the agents involved could be selected during its gestation. Although the initiative is apparently oriented towards developing individuals that would excel in society, critical voices raise the concerns about that this approach would generate and need for a reflection on the ethical, social and legal implications of these techniques and their implementation in society. We reviewed the literature about these issues throughout their historical records to date, focusing on the moral arguments and non-clinical aspects that affect the legal and social environment. We have observed various trends of thought with divergent positions (proactive, preventive, and regulatory) as well as a large number of articles that try to reconcile the different approaches. This review illustrates a series of concepts from the ethics and philosophy fields which are frequently used in studies that evaluate the ethical implications of germline genetic enhancement, such as dignity, benefit, autonomy, and identity. In addition, amongst the many unresolved controversies surrounding genetic enhancement, we identify procreative beneficence, genetic disassociation, gender selection, the value of disability, embryo chimerization, and the psychosocial inequality of potentially enhanced individuals as crucial. We also develop possible scenarios for future debate. We consider especially important the definition and specification of three aspects which are essential for the deployment of new reproductive technologies: the moral status of the embryo undergoing enhancement, the legal status of the enhanced individual, and the responsibility of the agents executing the enhancement. Finally, we propose the precautionary principle as a means to navigate ethical uncertainties.
dc.format	12
dc.format	application/pdf
dc.language	eng
dc.publisher	Frontiers Media
dc.relation	Frontiers in Genetics
dc.relation	10;
dc.rights	http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.rights	Attribution-NonCommercial-NoDerivatives 4.0 International
dc.rights	http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subject	Identitat (Concepte filosòfic)
dc.subject	Identity (Philosophical concept)
dc.subject	Identidad
dc.subject	Reproducció
dc.subject	Reproduction
dc.subject	Reproducción
dc.subject	ELSI
dc.subject	Millora genètica
dc.subject	Breeding
dc.subject	17
dc.subject	61
dc.title	Ethical challenges of germline genetic enhancement
dc.type	info:eu-repo/semantics/article
dc.type	info:eu-repo/semantics/acceptedVersion

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