RECERCAT Principal
>
Universitat Internacional de Catalunya
>
Recerca
>
Articles
>
Ciències de la Salut
>
Visualizar documento
Para acceder a los documentos con el texto completo, por favor, siga el siguiente enlace: http://hdl.handle.net/20.500.12328/1418
| dc.contributor.author | Truman, Andrew W. |
|---|---|
| dc.contributor.author | Kristjansdottir, Kolbrun |
| dc.contributor.author | Wolfgeher, Donald |
| dc.contributor.author | Ricco Pacheco, Natalia |
| dc.contributor.author | Mayampurath, Anoop |
| dc.contributor.author | Volchenboum, Samuel L. |
| dc.contributor.author | Clotet Erra, Josep |
| dc.contributor.author | Kron, Stephen J. |
| dc.date | 2020-01-04T14:32:52Z |
| dc.date | 2020-01-04T14:32:52Z |
| dc.date | 2015-03 |
| dc.identifier | Truman, Andrew W.; Kristjansdottir, Kolbrun; Wolfgeher, Donald [et al.]. The quantitative changes in the yeast Hsp70 and Hsp90 interactomes upon DNA damage. Data in Brief, 2015, vol. 2, p. 12-15. Disponible en: <https://www.sciencedirect.com/science/article/pii/S2352340914000249?via%3Dihub#t0005>. Fecha de acceso: 4 ene. 2020. DOI: 10.1016/j.dib.2014.10.006. |
| dc.identifier | 2352-3409 |
| dc.identifier | https://dx.doi.org/10.1016/j.dib.2014.10.006 |
| dc.identifier.uri | http://hdl.handle.net/20.500.12328/1418 |
| dc.description | The molecular chaperones Hsp70 and Hsp90 participate in many important cellular processes, including how cells respond to DNA damage. Here we show the results of applied quantitative affinity-purification mass spectrometry (AP-MS) proteomics to understand the protein network through which Hsp70 and Hsp90 exert their effects on the DNA damage response (DDR). We characterized the interactomes of the yeast Hsp70 isoform Ssa1 and Hsp90 isoform Hsp82 before and after exposure to methyl methanesulfonate. We identified 256 chaperone interactors, 146 of which are novel. Although the majority of chaperone interaction remained constant under DNA damage, 5 proteins (Coq5, Ast1, Cys3, Ydr210c and Rnr4) increased in interaction with Ssa1 and/or Hsp82. This data presented here are related to [1] (Truman et al., in press). The mass spectrometry proteomics data have been deposited to the ProteomeXchange Consortium (http://proteomecentral.proteomexchange.org) via the PRIDE partner repository (Vizcaino et al. (2013) [2]) with the dataset identifier PXD001284. |
| dc.format | 4 |
| dc.format | application/pdf |
| dc.language | eng |
| dc.publisher | Elsevier |
| dc.relation | Data in Brief |
| dc.relation | 2; |
| dc.rights | © 2014 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/3.0/). |
| dc.rights | http://creativecommons.org/licenses/by/3.0/ |
| dc.subject | ADN--Anàlisi |
| dc.subject | Molècules |
| dc.subject | Espectrometria de masses |
| dc.subject | ADN--Análisis |
| dc.subject | Moléculas |
| dc.subject | Espectrometría de masas |
| dc.subject | DNA--Analysis |
| dc.subject | Molecules |
| dc.subject | Mass spectrometry |
| dc.subject | 61 |
| dc.title | The quantitative changes in the yeast Hsp70 and Hsp90 interactomes upon DNA damage |
| dc.type | info:eu-repo/semantics/article |
| dc.type | info:eu-repo/semantics/acceptedVersion |
Documentos relacionados
Otros documentos del mismo autor/a
Ricco Pacheco, Natalia; Flor, Amy; Wolfgeher, Donald; Efimova, Elena V.; Ramamurthy, Aishwarya; Appelbe, Oliver K.; Brinkman, Jacqueline; Truman, Andrew W.; Spiotto, Michael T.; Kron, Stephen J.
Hernández Ortega, Sara; Sánchez Botet, Abril; Quandt Herrera, Eva; Masip, Núria; Gasa Colom, Laura; Verde, Gaetano; Jiménez Jiménez, Javier; Levin, Rebecca; Rugatanira, Florentine U.; Burlingame, Alma L.; Wolfgeher, Donald; P.C. Ribeiro, Mariana; Kron, Stephen J.; M. Shokat, Kevan; Clotet Erra, Josep
Samper Martín, Bàrbara; Sarrias, Ana; Lázaro, Blanca; Pérez-Montero, Marta; Rodríguez-Rodríguez, Rosalía; P.C. Ribeiro, Mariana; Bañón, Aitor; Wolfgeher, Donald; Jessen, Henning J.; Alsina, Berta; Clotet Erra, Josep; Kron, Stephen J.; Saiardi, Adolfo; Jiménez, Javier; Bru Rullo, Samuel
Ballega, Elisabet; Carballar Ruiz, María de los Reyes; Samper Martín, Bàrbara; Ricco Pacheco, Natalia; Ribeiro, Mariana P. C.; Bru Rullo, Samuel; Jiménez, Javier; Clotet Erra, Josep
Hernández-Ortega, Sara; Bru Rullo, Samuel; Ricco Pacheco, Natalia; Ramírez, Sara; Casals i Farré, Núria; Jiménez, Javier; Isasa, Marta; Crosas, Bernat; Clotet Erra, Josep