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Título:	Evaluation of bone loss in antibacterial coated dental implants: an experimental study in dogs
Autor/a:	Godoy Gallardo, María; Manzanares, Maria Cristina; Sevilla Sánchez, Pablo; Nart, José; Manzanares, Norberto; Manero Planella, José María; Gil Mur, Francisco Javier; Boyd, Steven K.; Rodríguez Rius, Daniel
Otros autores:	Universitat Politècnica de Catalunya. Departament de Ciència dels Materials i Enginyeria Metal·lúrgica; Universitat Politècnica de Catalunya. BBT - Biomaterials, Biomecànica i Enginyeria de Teixits; Universitat de Barcelona. Departament de Patologia i Terapèutica Experimental; University of Calgary. McCaig Institute for Bone and Joint Health
Abstract:	The aim of this study was to evaluate the in vivo effect of antibacterial modified dental implants in the first stages of peri-implantitis. Thirty dental implants were inserted in the mandibular premolar sites of 5 beagle dogs. Sites were randomly assigned to Ti (untreated implants, 10 units), Ti_Ag (silver electrodeposition treatment, 10 units), and Ti_TSP (silanization treatment, 10 units). Coated implants were characterized by scanning electron microscopy, interferometry and X-ray photoelectron spectroscopy. Two months after implant insertion, experimental peri-implantitis was initiated by ligature placement. Ligatures were removed 2 months later, and plaque formation was allowed for 2 additional months. Clinical and radiographic analyses were p¬erformed during the study. Implant-tissue samples were prepared for micro computed tomography, backscattered scanning electron microscopy, histomorphometric and histological analyses and ion release measurements. X-ray, SEM and histology images showed that vertical bone resorption in treated implants was lower than in the control group (P < 0.05). This effect is likely due to the capacity of the treatments to reduce bacteria colonization on the implant surface. Histological analysis suggested an increase of peri-implant bone formation on silanized implants. However, the short post-ligature period was not enough to detect differences in clinical parameters among implant groups. Within the limits of this study, antibacterial surface treatments have a positive effect against bone resorption induced by peri-implantitis.
Abstract:	Peer Reviewed
Materia(s):	-Àrees temàtiques de la UPC::Enginyeria dels materials -Dental implants -Biomedical materials -Antibacterial agents -Antibacterial coating -dental implants -in vivo -peri-implantitis -silver electrodeposition -TESPSA -Pròtesis dentals -Materials biomèdics -Gossos -- Malalties
Derechos:	http://creativecommons.org/licenses/by-nc-nd/3.0/es/
Tipo de documento:	Artículo - Versión presentada Artículo
Editor:	Elsevier
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