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Leveraging 6LoWPAN, the IETF 6Lo Working Group has targeted adaptation of IPv6 over a new generation of communication technologies for the IoT. These comprise Bluetooth LE, ITU-T G.9959, DECT ULE, MS/TP, NFC, IEEE 1901.2, and IEEE 802.11ah. This article comprehensively analyzes the 6Lo technologies and adaptation layers, giving the motivation for critical design decisions, highlighting crucial aspects for performance, and presenting main challenges.