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Title:
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Surface tension controls the hydraulic fracture of adhesive interfaces bridged by molecular bonds
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Author:
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Kaurin, Dimitri Jean Antoine; Arroyo Balaguer, Marino
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Other authors:
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Universitat Politècnica de Catalunya. Departament d'Enginyeria Civil i Ambiental; Universitat Politècnica de Catalunya. LACÀN - Mètodes Numèrics en Ciències Aplicades i Enginyeria |
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Abstract:
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Biological function requires cell-cell adhesions to tune their cohesiveness; for instance, during the opening of new fluid-filled cavities under hydraulic pressure. To understand the physical mechanisms supporting this adaptability, we develop a stochastic model for the hydraulic fracture of adhesive interfaces bridged by molecular bonds. We find that surface tension strongly enhances the stability of these interfaces by controlling flaw sensitivity, lifetime, and optimal architecture in terms of bond clustering. We also show that bond mobility embrittles adhesions and changes the mechanism of decohesion. Our study provides a mechanistic background to understand the biological regulation of cell-cell cohesion and fracture. |
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Abstract:
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Peer Reviewed |
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Subject(s):
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-Àrees temàtiques de la UPC::Matemàtiques i estadística::Anàlisi numèrica::Mètodes numèrics
-Àrees temàtiques de la UPC::Matemàtiques i estadística::Matemàtica aplicada a les ciències
-Numerical analysis--Simulation methods
-Fracture mechanics
-Anàlisi numèrica
-Mecànica de fractura
-Classificació AMS::65 Numerical analysis::65C Probabilistic methods, simulation and stochastic differential equations
-Classificació AMS::74 Mechanics of deformable solids::74R Fracture and damage |
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Rights:
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Document type:
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Article - Submitted version
Article |
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Published by:
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American Institute of Physics (AIP)
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