Vall d'Hebron Institut d'Oncologia – VHIO

Recent Submissions

USP10/GSK3β-mediated inhibition of PTEN drives resistance to PI3K inhibitors in breast cancer 

Kumari, Nishi; Wright, Sarah Christine Elisabeth; Witham, Christopher; Monserrat, Laia; Palafox Sánchez, Marta; Richard, John L. C.; Serra, Violeta (2025-11-25)

Breast cancer; Cell biology; Oncology

Atezolizumab, bevacizumab, and platinum chemotherapy in cervical cancer: results of Japanese population from BEATcc 

Takekuma, Munetaka; Nishio, Shin; Yamaguchi, Satoshi; Yunokawa, Mayu; Nishio, Hiroshi; Nishino, Koji; Villacampa Javierre, Guillermo; OAKNIN, ANA (2025-11-24)

Angiogenesis Inhibitors; Atezolizumab; Bevacizumab

Breastfeeding after breast cancer in young BRCA carriers 

DELUCCHI, VIRGINIA; Ferrari, Alberta; Blondeaux, Eva; Mariamidze, Elene; Bernstein Molho, Rinat; Frank, Sophie; Balmaña, Judith (2025-11-24)

Breastfeeding; Breast cancer; BRCA carriers

Cabozantinib plus Atezolizumab in Advanced, Progressive Endocrine Malignancies: A Multicohort, Basket, Phase II Trial (CABATEN/GETNE-T1914) 

Hernando, Jorge; BENAVENT VIÑUALES, MARTA; Capdevila Castillon, Jaume; Molina-Cerrillo, Javier; Garcia-Carbonero, Rocio; Teule, Alex (2025-11-21)

Cabozantinib; Atezolizumab; Advanced progressive endocrine malignancies

Randomized clinical efficacy and safety study of peltopepimut-S plus cemiplimab compared to cemiplimab alone in patients with recurrent/metastatic HPV16-positive head and neck cancer 

Even, Caroline; Massarelli, Erminia; Laban, Simon; FAYETTE, Jérôme; Oliva Bernal, Marc; Harrington, Kevin; Brana, Irene (2025-11-11)

Combination therapy; Head and neck cancer; Immune checkpoint inhibitor

Retreatment with oxaliplatin-based regimens in refractory metastatic colorectal cancer: characterization of high-response patients 

Catani, Greta; Alcaraz Soler, Adriana; García, Ariadna I.; Elez, Elena; Salvà, Francesc; Saoudi Gonzalez, Nadia; Baraibar, Iosune; Ros, Javier; R Castells, Marta; Salva de Torres, Clara; Comas Navarro, Raquel; Ruiz Pace, Fiorella; Rezqallah Arón , María Alejandra; Dienstmann, Rodrigo; Tabernero, Josep (2025-11-10)

Oxaliplatin; Rechallenge; Reintroduce

Preoperative immunotherapy with atezolizumab and tiragolumab in patients with colorectal liver metastases—the PURPLE trial 

Elez, Elena; Neumann, Ulf; Lang, Sven Arke; Trampe, A. K.; Kasper, Stefan; Salvà, Francesc (2025-11-07)

Colorectal liver metastases; Preoperative immunotherapy; Atezolizumab

GOG-3097/ENGOT-ov81/GTG-UK/RAMP 301: a phase 3, randomized trial evaluating avutometinib plus defactinib compared with investigator’s choice of treatment in patients with recurrent low grade serous ovarian cancer 

Moore, Kathleen; FABBRO, MICHEL; OMalley, David; Grisham, Rachel; Monk, Bradley; Van Nieuwenhuysen, Els (2025-11-06)

Ovarian Cancer

Clinical validation of liquid biopsy-RECIST (LB-RECIST) in metastatic colorectal cancer (mCRC) patients: findings from the PLATFORM-B study 

MARTELLI, VALENTINO; vidal barrull, joana; Gibert Fernandez, Joan; Fernandez-Rodriguez, Concepción; Linares, Jenniffer; Elez, Elena; García-Alfonso, Pilar; Toledo, Rodrigo; Tabernero, Josep (2025-11-05)

Liquid biopsy; Metastatic colorectal cancer; Response assessment

Epigenetic synthetic lethality as a cancer therapeutic strategy: synergy of experimental and computational approaches 

Fariña Morillas, Maria; Ollé i Monràs, Laia; de Rojas de Pablo, Isabel; Seoane Fernández, Jose Antonio; Maas, Silvana; Segura, Miguel F. (2025-11-03)

Synthetic lethality; Chromatin remodeling; Epidrugs

Randomised trial of trastuzumab deruxtecan and biology-driven selection of neoadjuvant treatment for HER2-positive breast cancer: a study protocol of ARIADNE 

Naume, Bjørn; wildiers, hans; Sonke, Gabe; Karakatsanis, Andreas; Matikas, Alexios; DIECI, MARIA VITTORIA; Villacampa Javierre, Guillermo (2025-10-30)

Breast tumours; Drug therapy

Spatial TCR clonality and clonal expansion in the in situ microenvironment of non-small cell lung cancer 

Yu, Hui; Magoulopoulou, Anastasia; Amini, Rose-Marie; Chatzinikolaou, Maria Paraskevi; Horie, Masafumi; Lindberg, Amanda; Mezheyeuski, Artur (2025-10-30)

Clonality; Immune Checkpoint Inhibitor; Lung Cancer

Metabolic dysfunction-associated steatohepatitis reduces hepatic H2S-producing enzymes altering persulfidome composition 

SHEN, TZU-KENG; Vignane, Thibaut; Gilglioni, Eduardo Hideo; Traini, Leonardo; Kalaitsidou, Elisavet; Conan, Pierre; Herranz Alzueta, Jose Mari (2025-10-30)

Steatohepatitis; Metabolic dysfunction; Persulfidome

Fusobacterium nucleatum interacts with cancer-associated fibroblasts to promote colorectal cancer 

Karta, Jessica; Meyers, Marianne; Rodriguez, Fabien; Koncina, Eric; Gilson, Cédric; Klein, Eliane; Alonso Landeira, Lidia; Aguilera Pujabet, Mònica; Nuciforo, Paolo (2025-10-30)

Fusobacterium nucleatum; Cancer-associated fibroblasts; Colorectal Cancer

Clinical Validity of FoundationOne Liquid CDx for Detection of BRAFV600E in Colorectal Cancer 

Martini, Jean-Francois; Pasquina, Lincoln; Tunquist, Brian; Zhang, Xiaosong; Khaiser, Fatima; Yaeger, Rona; Tabernero, Josep (2025-10-29)

BRAF inhibitor; Colorectal cancer

Optimization and validation of the international metabolic prognostic index for CD19 CAR-T in large B-cell lymphoma 

Winkelmann, Michael; Raj, Sandeep S.; Müller, Fabian; Hansmann, Leo; Jain, Michael; IACOBONI, GLORIA; Barba, Pere (2025-10-29)

Metabolic prognostic index; CD19 CAR-T; Large B-cell lymphoma

White paper on best practices for translational research in neuroendocrine neoplasms 

Cros, Jerome; Casanovas, Oriol; Castaño, Justo P.; Dayton, Talya; GIBERT, Benjamin; Garcia-Alvarez, Alejandro (2025-10-29)

Carcinoids; Genomics; Liquid biopsy

Human Microbiota and Breast Cancer—Is There Any Relevant Link?—A Literature Review and New Horizons Toward Personalised Medicine 

Alpuim Costa, Diogo; Nobre, José Guilherme; Ribeiro, Catarina; Calle, Catarina; Cortés, A.; Cortés Castan, Javier; Vaz Batista, Marta (2022-06-08)

Breast cancer; Personalized medicine; Pharmacomicrobiomics

Recommendations for the use of next-generation sequencing (NGS) for patients with advanced cancer in 2024: a report from the ESMO Precision Medicine Working Group 

Mosele, Maria; Stenzinger, Albrecht; Bayle, Arnaud; Bieche, Ivan; Westphalen, Benedikt; Barlesi, Fabrice; Dienstmann, Rodrigo; Serrano, Cesar; Mateo, Joaquin (2024-06-27)

Advanced cancer; Next-generation sequencing; Precision medicine

Genetic immune escape landscape in primary and metastatic cancer 

Martínez-Jiménez, Francisco; Priestley, Peter; Shale, Charles; Baber, Jonathan; Rozemuller, Erik; Cuppen, Edwin (2023-07-04)

Genome; Tumour immunology