Minimum information about tolerogenic antigen-presenting cells (MITAP): a first step towards reproducibility and standardisation of cellular therapies

dc.contributor.author
Lord, Phillip
dc.contributor.author
Spiering, Rachel
dc.contributor.author
Aguillon, Juan C.
dc.contributor.author
Anderson, Amy E.
dc.contributor.author
Appel, Silke
dc.contributor.author
Benítez Ribas, Daniel
dc.contributor.author
Brinke, Anja ten
dc.contributor.author
Broere, Femke
dc.contributor.author
Cools, Nathalie
dc.contributor.author
Cuturi, Maria Cristina
dc.contributor.author
Diboll, Julie
dc.contributor.author
Geissler, Edward K.
dc.contributor.author
Giannoukakis, Nick
dc.contributor.author
Gregori, Silvia
dc.contributor.author
Ham, S. Marieke van
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Lattimer, Staci
dc.contributor.author
Marshall, Lindsay
dc.contributor.author
Harry, Rachel A.
dc.contributor.author
Hutchinson, James A.
dc.contributor.author
Isaacs, John
dc.contributor.author
Joosten, Irma
dc.contributor.author
Kooten, Cees van
dc.contributor.author
López Díaz de Cerio, Ascensión
dc.contributor.author
Nikolic, Tatjana
dc.contributor.author
Oral, Haluk Barbaros
dc.contributor.author
Sofronic-Milosavljevic, Ljiljana
dc.contributor.author
Ritter, Thomas
dc.contributor.author
Riquelme, Paloma
dc.contributor.author
Thomson, Angus W.
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Trucco, Massimo
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Vives Pi, Marta
dc.contributor.author
Martínez Cáceres, Eva María
dc.contributor.author
Hilkens, Catharien M. U.
dc.date.issued
2016
dc.identifier
https://ddd.uab.cat/record/174667
dc.identifier
urn:10.7717/peerj.2300
dc.identifier
urn:oai:ddd.uab.cat:174667
dc.identifier
urn:pmid:27635311
dc.identifier
urn:articleid:21678359v4e2300
dc.identifier
urn:scopus_id:84992127794
dc.identifier
urn:wos_id:000383262700002
dc.identifier
urn:altmetric_id:10903543
dc.identifier
urn:oai:egreta.uab.cat:publications/35be77a3-c13b-4c44-9c17-efd20ede799b
dc.identifier
urn:pmc-uid:5012269
dc.identifier
urn:pmcid:PMC5012269
dc.identifier
urn:oai:pubmedcentral.nih.gov:5012269
dc.description.abstract
Altres ajuts: COST/AFACTT/BM1305
dc.description.abstract
Cellular therapies with tolerogenic antigen-presenting cells (tolAPC) show great promise for the treatment of autoimmune diseases and for the prevention of destructive immune responses after transplantation. The methodologies for generating tolAPC vary greatly between different laboratories, making it difficult to compare data from different studies; thus constituting a major hurdle for the development of standardised tolAPC therapeutic products. Here we describe an initiative by members of the tolAPC field to generate a minimum information model for tolAPC (MITAP), providing a reporting framework that will make differences and similarities between tolAPC products transparent. In this way, MITAP constitutes a first but important step towards the production of standardised and reproducible tolAPC for clinical application.
dc.format
application/pdf
dc.language
eng
dc.publisher
dc.relation
PeerJ ; Vol. 4 (August 2016), p. e2300
dc.rights
open access
dc.rights
Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
dc.rights
https://creativecommons.org/licenses/by/4.0/
dc.subject
Antigen-presenting cells
dc.subject
Autoimmune disease
dc.subject
Cell therapy
dc.subject
Minimum information model
dc.subject
Regulatory macrophages
dc.subject
Reporting guidelines
dc.subject
Tolerogenic dendritic cells
dc.subject
Transplantation
dc.title
Minimum information about tolerogenic antigen-presenting cells (MITAP): a first step towards reproducibility and standardisation of cellular therapies
dc.type
Article


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