Asthma control and COPD symptom burden in patients using fixed-dose combination inhalers (SPRINT study)

Author

Roche, Nicolas

Plaza, Vicente

Backer, Vibeke

van der Palen, Job

Cerveri, Isa

Gonzalez, Chelo

Safioti, Guilherme

Scheepstra, Irma

Patino, Oliver

Singh, Dave

Universitat Autònoma de Barcelona

Publication date

2020

Abstract

Altres ajuts: Medical writing support was provided by Ian Grieve of Ashfield Healthcare Communications, part of UDG Healthcare plc, and was funded by Teva Pharmaceuticals.


Previous studies have found suboptimal control of symptom burden to be widespread among patients with asthma and chronic obstructive pulmonary disease (COPD). The Phase IV SPRINT study was conducted in 10 countries in Europe to assess asthma disease control and COPD symptom burden in patients treated with a fixed-dose combination (FDC) of inhaled corticosteroids (ICS) and long-acting beta agonists (LABAs). SPRINT included 1101 patients with asthma and 560 with COPD; all were receiving treatment with an FDC of ICS/LABA, delivered via various inhalers. Data were obtained over a 3-month period, during a single routine physician's office visit. Asthma control was defined as Asthma Control Test (ACT) score >19. COPD symptom burden was assessed by COPD Assessment Test (CAT), with a CAT score <10 defining low COPD symptom burden. Among patients using any ICS/LABA FDC, 62% of patients with asthma had achieved disease control (ACT score >19) and 16% of patients with COPD had low symptom burden (CAT score <10).

Document Type

Article

Language

English

Subjects and keywords

Therapeutics; Health care

Publisher

 

Related items

NPJ primary care respiratory medicine ; Vol. 30 (january 2020)

Rights

open access

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