Articles publicats Departament de Biologia

Universitat de Girona Facultat de Lletres

La Universitat de Girona és una institució pública que cerca l’excel·lència en la docència i en la recerca, i que participa en el progrés i el desenvolupament de la societat, mitjançant la creació, transmissió, difusió i crítica de la ciència, la tècnica, les humanitats, les ciències socials i les arts.La Universitat de Girona està arrelada al país i a la cultura catalana i és un dels principals motors econòmics i culturals del seu entorn. Al mateix temps, expressa la vocació d’universalitat i d’obertura a totes les tradicions, avenços i cultures.La Universitat té la seva seu a la ciutat de Girona i s’integra en el sistema d’universitats públiques catalanes.


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Recent Submissions

Tracking Age-Linked Antibiotic Resistance Patterns through Building-Level Wastewater Analysis 

Pico-Tomàs, Anna; Sanchís, Alejandro; Mejías Molina, Cristina; Comas Cufí, Marc; Balcázar, José Luis; Bofill Mas, Silvia; Torrell, Helena; Canela, Núria; Borrego i Moré, Carles; Corominas Tabares, Lluís (2025-11-07)

Antimicrobial resistance (AMR) is a global health challenge, and monitoring different demographic populations can improve our understanding of its spread and prevalence in urban settlements. This study applies building-level ...

Red LED light irradiation increases the resistance against environmental stress of frozen bovine sperm thawed in suboptimal conditions 

Blanco Prieto, Olga; Maside, Carolina; Gruzmacher, Andrea; Ortiz, Manuel; Ratto, Marcelo; Urra, Francisco Javier; Vera, Tomás; Strobel, Pablo; Catalán, Jaime; Mislei, Beatrice; Bucci, Diego; Yeste Oliveras, Marc; Rodríguez Gil, Joan Enric; Ramírez-Reveco, A. (2025-11-20)

This work sought to test the positive effect of red LED light on frozen bovine sperm resistance to thawing in suboptimal conditions. Moreover, a preliminary study explores whether this improvement could have any repercussions ...

Genome sequencing and analysis of black flounder (Paralichthys orbignyanus) reveals new insights into Pleuronectiformes genomic size and structure 

Villarreal, Fernando; Burguener, Germán F.; Sosa, Ezequiel J.; Stocchi, Nicolas; Somoza, Gustavo M.; Turjanski, Adrián G.; Blanco, Andrés; Viñas de Puig, Jordi; Mechaly, Alejandro S. (2024-03-20)

Black flounder (Paralichthys orbignyanus, Pleuronectiformes) is a commercially significant marine fish with promising aquaculture potential in Argentina. Despite extensive studies on Black flounder aquaculture, its limited ...

Association between the adherence to different dietary patterns and sperm chromatin integrity in healthy men 

Llavanera, Marc; Puente, María Fernández de la; Davila-Cordova, Estefanía; Eigbefoh-Addeh, Ailende; Agarwal, Rashmi; Valle-Hita, Cristina; Babio, Nancy; Salas Salvadó, Jordi; Yeste Oliveras, Marc; Salas Huetos, Albert (2025-10-18)

Research Question: Are healthy and unhealthy diets associated with sperm DNA fragmentation and chromatin deprotamination in healthy men of reproductive age? Design: A cross-sectional analysis conducted using healthy male ...

Intracranial self-stimulation mitigates spatial task deficits, modifies miR-146a and miR-495 serum levels and restores hippocampal NRF2 levels in a rat model of sporadic Alzheimer's disease 

Riberas Sánchez, Andrea; García-Brito, Soleil; Vila-Solés, Laia; Aldavert Vera, Laura; Segura i Torres, Pilar; Huguet i Blanco, Gemma; Carreras Badosa, Gemma; Kádár García, Elisabeth (2025-11-11)

INTRODUCTION: A definitive diagnosis of Alzheimer's disease (AD) requires the identification of pathological changes. Plasma miRNAs have emerged as potential AD diagnostic biomarkers. METHODS: Amatched case-control study ...

Photoinduced electron transfer enhances the tumor-targeted photodynamic activity of bombesin metallopeptides incorporating an Ir(III) complex and carboxyfluorescein 

Zafon, Elisenda; Riesco-Llach, Gerard; Echevarría Poza, Igor; Martínez Alonso, Marta; Feliu Soley, Lidia; Espino Ordóñez, Gustavo; Massaguer i Vall-llovera, Anna (2025-11)

A primary objective of photodynamic therapy (PDT) is to develop tumor-targeted photosensitizers (PS) that enable selective cytotoxicity through preferential accumulation in cancer tissues and local activation by light. ...

The multiomics blueprint of the individual with the most extreme lifespan 

Santos-Pujol, Eloy; Noguera Castells, Aleix; Casado-Pelaez, Marta; García-Prieto, Carlos A.; Vasallo, Claudia; Campillo-Marcos, Ignacio; Quero-Dotor, Carlos; Crespo Garcia, Eva; Bueno-Costa, Alberto; Setién, Fernando; Ferrer, Gerardo; Davalos, Veronica; Mereu, Elisabetta; Pluvinet, Raquel; Arribas, Carles; Torre, Carolina de la; Villavicencio, Francisco; Sumoy, Lauro; Granada, Isabel; Coles, Natalie S.; Acha, Pamela; Solé, Francesc; Mallo, Mar; Mata, Caterina; Peregrina, Sara; Gabaldón, Toni; Llirós Dupré, Marc; Pujolassos, Meritxell; Carreras-Torres, Robert; Lluansí Salis, Aleix; Garcia-Gil, L. J.; Aldeguer i Manté, Xavier; Samino, Sara; Torné, Pol; Ribalta, Josep; Guardiola, Montse; Amigó, Núria; Yanes, Oscar; Martínez, Paula; Sánchez-Vázquez, Raúl; Blasco, Maria A.; Oviedo, José; Lemos, Bernardo; Rius Bonet, Júlia; Torrubiano, Marta; Massip-Salcedo, Marta; Khidir, Kamal A.; Cao, Thong H.; Quinn, Paulene A.; Jones, Donald J.L.; Macip, Salvador; Brigos Barril, Eva; Moldes, Maurici; Barteri, Fabio; Muntané, Gerard; Laayouni, Hafid; Navarro, Arcadi; Esteller, Manel (2025-10-21)

Extreme human lifespan, exemplified by supercentenarians, presents a paradox in understanding aging: despite advanced age, they maintain relatively good health. To investigate this duality, we have performed a high-throughput ...

Intracranial self-stimulation reverses impaired spatial learning and regulates serum microRNA levels in a streptozotocin-induced rat model of Alzheimer disease 

Riberas Sánchez, Andrea; Puig Parnau, Irene; Vila-Solés, Laia; García-Brito, Soleil; Aldavert Vera, Laura; Segura Torres, Pilar; Huguet i Blanco, Gemma; Kádár García, Elisabeth (2024-03-15)

Background: The assessment of deep brain stimulation (DBS) as a therapeutic alternative for treating Alzheimer disease (AD) is on-going. We aimed to determine the effects of intracranial self-stimulation at the medial ...

Blastocoel fluid aspiration improves vitrification outcomes and produces similar sexing results of in vitro-produced cattle embryos compared to microblade biopsy 

Martínez Rodero, Iris; Salas Huetos, Albert; Diaz-Muñoz, Judith; Ordóñez León, Erika Alina; García Martínez, Tania; Yeste Oliveras, Marc; Hidalgo Ordoñez, Carlos Olegario; Mogas Amorós, Teresa (2024-04-01)

The potential applications of in vitro-produced (IVP) cattle embryos are significantly enhanced when combined with genotype selection and cryopreservation techniques. While trophectoderm (TE) biopsies are frequently used ...

Editorial: Mucosal immunity after vaccination 

Arish, Mohd; López Siles, Mireia; Naz, Farha (2025-09-05)

The mucosal immune system is the largest immunological interface with the environment in our body. On the one hand, it contributes to the preservation of commensal microbiota by several mechanisms such production of secretory ...

Identification of a Differential Microbiological Signature of Extended‐Spectrum ß‐Lactamases Producing Escherichia Carriers in Spanish Community Children 

Cardinali-Benigni, Martina; Khannous-Lleiffe, Olfat; Saus, Ester; Carmena, David; McConnell, Michael J.; Gabaldón, Toni; López Siles, Mireia (2025-12)

Gut colonization by Extended-spectrum ß-lactamase-producing Enterobacteriaceae (ESBL-E), is increasing among nonhospitalized children, but the impact of ESBL-E carriage on the intestinal microbiota remains unknown. In this ...

Acinetobacter baumannii as a Model for the Study and Application of Gram-negative Outer Membrane Vesicles: A Systematic Review 

Cano Castaño, Beatriz; López Siles, Mireia; Nonnoi, Francesca; Pérez, Astrid; Corral Lugo, Andrés; McConnell, Michael J. (2025-09-04)

Outer membrane vesicles (OMVs) are extracellular nanostructures released from Gram-negative bacteria. Acinetobacter baumannii OMVs (AbOMVs) have been extensively studied and can thus be used as a model for understanding ...

Rational design of mitochondria targeted thiabendazole-based Ir(III) biscyclometalated complexes for a multimodal photodynamic therapy of cancer 

Echevarría Poza, Igor; Zafon, Elisenda; Barrabés Vera, Sílvia; Martínez, María Ángeles; Ramos Gómez, Sonia; Ortega Santamaría, Natividad; Manzano, Blanca R.; Jalón, Félix A.; Quesada Pato, Roberto; Espino Ordóñez, Gustavo; Massaguer i Vall-llovera, Anna (2022-06-01)

Despite their outstanding properties as potential photosensitizers for photodynamic therapy (PDT), Ir(III) biscyclometalated complexes need both further developments to overcome remaining limitations and in-depth investigations ...

Luminescent cyclometalated platinum compounds with N, P, and O^O ligands: Density-functional theory studies and analysis of the anticancer potential 

Leal, Jorge; Durá, Gema; Jalón, Félix A.; Zafon, Elisenda; Massaguer i Vall-llovera, Anna; Cuevas-Vicario, José Vicente; Santos Peinado, Lucía; Rodríguez, Ana María Blanco; Manzano, Blanca R. (2023-03-01)

Luminescent platinum cyclometalated complexes are species of interest mainly due to their applications in the optoelectronic and biological fields, especially with regard to their anticancer activity. Given this level of ...

Ir(III) Half-Sandwich Photosensitizers with a π-Expansive Ligand for Efficient Anticancer Photodynamic Therapy 

Gonzalo-Navarro, Carlos; Zafon, Elisenda; Organero Gallego, Juan Ángel; Jalón, Félix A.; Lima, Joao Carlos; Espino Ordóñez, Gustavo; Rodríguez, Ana María Blanco; Santos Peinado, Lucía; Moro, Artut J.; Barrabés Vera, Sílvia; Castro Gallegos, Jessica; Camacho-Aguayo, Javier; Massaguer i Vall-llovera, Anna; Manzano, Blanca R.; Durá, Gema (2024-01-30)

One approach to reduce the side effects of chemotherapy in cancer treatment is photodynamic therapy (PDT), which allows spatiotemporal control of the cytotoxicity. We have used the strategy of coordinating π-expansive ...

Ru-terpyridine complexes containing clotrimazole as potent photoactivatable selective antifungal agents 

Gonzalo-Navarro, Carlos; Troyano Saez, Antonio J.; García-Béjar Bermejo, Beatriz Bermejo; Organero Gallego, Juan Ángel; Massaguer i Vall-llovera, Anna; Santos Peinado, Lucía; Rodríguez Fernández-Pacheco, Ana María; Manzano, Blanca R.; Durá, Gema (2024-11)

The overuse of antimicrobial agents in medical and veterinary applications has led to the development of antimicrobial resistance in some microorganisms and this is now one of the major concerns in modern society. In this ...

Phenotypic plasticity in the health status of western Mediterranean sardines. Estimation of spawning quantity and quality 

Frigola-Tepe, Xènia; Ollé Vilanova, Judith; Schull, Quentin; Caballero Huertas, Marta; Viñas de Puig, Jordi; Muñoz Frigola, Marta (2023)

The European sardine exhibits drastic changes in body condition, growth, and reproduction outputs with fluctuating environments, leading to trade-offs in life history traits. This study aimed to compare the health status ...

Environmental contamination and male reproductive health: (ir)reversible effects in child- and adulthood 

Corcini, Carine Dahl; Varela Junior, Antonio Sergio; Yeste Oliveras, Marc (2025-03-21)

Infertility affects 10-15% of reproductive-age couples, with causes ranging from genetic factors to unidentified reasons. Environmental conditions, particularly pollutants, play a significant role in male fertility. Yet, ...

Protective role of extracellular vesicles against oxidative DNA damage 

Ribas Maynou, Jordi; Parra, Ana; Martínez-Díaz, Pablo; Peres Rubio, Camila; Lucas, Xiomara; Yeste Oliveras, Marc; Roca, Jordi; Barranco, Isabel (2025-03-13)

Background: Oxidative stress, a source of genotoxic damage, is often the underlying mechanism in many functional cell disorders. Extracellular vesicles (EVs) have been shown to be key regulators of cellular processes and ...

Decoding a novel non-enzymatic protein acetylation mechanism in sperm that is essential for fertilizing potential 

Iniesta-Cuerda, María; Nevoral, Jan; Krapf, Dario; Garde, Julián; Soler-Valls, Ana Josefa; Yeste Oliveras, Marc (2025-05-29)

Background: Protein acetylation has emerged as essential for sperm function, attracting considerable attention recently. Acetylation, typically mediated by lysine acetyltransferases, involves attaching an acetyl group from ...

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