dc.contributor.author |
Montull Veiga, Beatriz |
dc.contributor.author |
Menéndez Villanueva, Rosario |
dc.contributor.author |
Torres, Antoni |
dc.contributor.author |
Reyes Calzada, Soledad María |
dc.contributor.author |
Méndez, Raúl |
dc.contributor.author |
Zalacaín, Rafael |
dc.contributor.author |
Capelastegui, Alberto |
dc.contributor.author |
Rajas, Olga |
dc.contributor.author |
Borderías, Luis |
dc.contributor.author |
Martín Villasclaras, Juan |
dc.contributor.author |
Bello, Salvador |
dc.contributor.author |
Alfageme, Inmaculada |
dc.contributor.author |
Rodríguez de Castro, Felipe |
dc.contributor.author |
Rello, Jordi |
dc.contributor.author |
Molinos, Luis |
dc.contributor.author |
Ruiz Manzano, Juan |
dc.date |
2016 |
dc.identifier |
https://ddd.uab.cat/record/174683 |
dc.identifier |
urn:10.1371/journal.pone.0145929 |
dc.identifier |
urn:oai:ddd.uab.cat:174683 |
dc.identifier |
urn:pmid:26727202 |
dc.identifier |
urn:scopus_id:84954069531 |
dc.identifier |
urn:wos_id:000367681500036 |
dc.identifier |
urn:altmetric_id:4954694 |
dc.identifier |
urn:oai:egreta.uab.cat:publications/4f83125d-3676-4ee1-930c-6ef86149c906 |
dc.identifier |
urn:pmc-uid:4699794 |
dc.identifier |
urn:pmcid:PMC4699794 |
dc.identifier |
urn:oai:pubmedcentral.nih.gov:4699794 |
dc.format |
application/pdf |
dc.language |
eng |
dc.publisher |
|
dc.relation |
Instituto de Salud Carlos III PI04/1150 |
dc.relation |
PloS one ; Vol. 11 Núm. 1 (January 2016) |
dc.rights |
open access |
dc.rights |
Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original. |
dc.rights |
https://creativecommons.org/licenses/by/4.0/ |
dc.subject |
Community-acquired pneumonia |
dc.subject |
Predictors |
dc.subject |
Severe sepsis |
dc.title |
Predictors of severe sepsis among patients hospitalized for community-acquired pneumonia |
dc.type |
Article |
dc.description.abstract |
This work was supported by PII (Programme of research of SEPAR) in respiratory infection; CIBERES (Centro de investigación en red de enfermedades respiratorias) an initiative of ISCIII (Instituto de Salud Carlos III); Beca Fis (PI04/1150); Beca SEPAR (Sociedad Española de Neumología y Cirugía torácica) (2006/0237) and Beca de la Consellería Sanitat Comunidad Valenciana (2007/ 0059). |
dc.description.abstract |
Altres ajuts: SEPAR/2006/0237 |
dc.description.abstract |
Background: Severe sepsis, may be present on hospital arrival in approximately one-third of patients with community-acquired pneumonia (CAP). Objective: To determine the host characteristics and micro-organisms associated with severe sepsis in patients hospitalized with CAP. Results: We performed a prospective multicenter cohort study in 13 Spanish hospital, on 4070 hospitalized CAP patients, 1529 of whom (37.6%) presented with severe sepsis. Severe sepsis CAP was independently associated with older age (>65 years), alcohol abuse (OR, 1.31; 95% CI, 1.07-1.61), chronic obstructive pulmonary disease (COPD) (OR, 1.75; 95% CI, 1.50-2.04) and renal disease (OR, 1.57; 95% CI, 1.21-2.03), whereas prior antibiotic treatment was a protective factor (OR, 0.62; 95% CI, 0.52-0.73). Bacteremia (OR, 1.37; 95% CI, 1.05-1.79), S pneumoniae (OR, 1.59; 95% CI, 1.31-1.95) and mixed microbial etiology (OR, 1.65; 95% CI, 1.10-2.49) were associated with severe sepsis CAP. Conclusions: CAP patients with COPD, renal disease and alcohol abuse, as well as those with CAP due to S pneumonia or mixed micro-organisms are more likely to present to the hospital with severe sepsis. |