dc.contributor
Universitat Politècnica de Catalunya. Departament de Ciència dels Materials i Enginyeria Metal·lúrgica
dc.contributor
Institut de Bioenginyeria de Catalunya
dc.contributor
Universitat Politècnica de Catalunya. BBT - Biomaterials, Biomecànica i Enginyeria de Teixits
dc.contributor.author
Rodríguez-Seguí, S.A.
dc.contributor.author
Pla-Roca, M.
dc.contributor.author
Engel López, Elisabeth
dc.contributor.author
Planell Estany, Josep Anton
dc.contributor.author
Martínez, E.
dc.contributor.author
Samitier Martí, Josep
dc.identifier
Rodríguez-Seguí, S. [et al.]. Influence of fabrication parameters on cellular microarrays for stem cell studies. "Journal of materials science. Materials in medicine", 2009, vol. 20, núm. 7, p. 1525-1533.
dc.identifier
https://hdl.handle.net/2117/26641
dc.identifier
10.1007/s10856-009-3716-2
dc.description.abstract
Lately there has been an increasing interest in
the development of tools that enable the high throughput
analysis of combinations of surface-immobilized signaling
factors and which examine their effect on stem cell biology
and differentiation. These surface-immobilized factors
function as artificial microenvironments that can be
ordered in a microarray format. These microarrays could be
useful for applications such as the study of stem cell
biology to get a deeper understanding of their differentia-
tion process. Here, the evaluation of several key process
parameters affecting the cellular microarray fabrication is
reported in terms of its effects on the mesenchymal stem
cell culture time on these microarrays. Substrate and pro-
tein solution requirements, passivation strategies and cell
culture conditions are investigated. The results described in
this article serve as a basis for the future development of
cellular microarrays aiming to provide a deeper under-
standing of the stem cell differentiation process.
dc.description.abstract
Peer Reviewed
dc.description.abstract
Postprint (published version)
dc.format
application/pdf
dc.rights
http://creativecommons.org/licenses/by-nc-nd/3.0/es/
dc.rights
Restricted access - publisher's policy
dc.rights
Attribution-NonCommercial-NoDerivs 3.0 Spain
dc.subject
Àrees temàtiques de la UPC::Enginyeria dels materials
dc.subject
DNA microarrays
dc.subject
Microxips d'ADN
dc.title
Influence of fabrication parameters on cellular microarrays for stem cell studies
