dc.contributor.author
Quiroga, Andres
dc.contributor.author
Cortese, Lorenzo
dc.contributor.author
Verma, Manish
dc.contributor.author
Dannberg, Peter
dc.contributor.author
Tachtsidis, Ilias
dc.contributor.author
Danz, Norbert
dc.contributor.author
Durduran, Turgut
dc.date.issued
2025-10-01
dc.identifier
Quiroga, A. [et al.]. On-skin, micro-objective enabled camera module for speckle contrast optical spectroscopy/tomography. Optica, 2025. DOI 10.1364/BOE.571276 .
dc.identifier
https://hdl.handle.net/2117/448544
dc.identifier
10.1364/BOE.571276
dc.description.abstract
In this paper, we introduce a speckle contrast optical spectroscopy/tomography (SCOS/SCOT) configuration based on an integrated imaging approach exploiting 113 microobjectives mounted on a commercial CMOS camera that operates without fiber coupling, suitable for direct skin contact measurements and simultaneous multiple source-detector separation acquisitions. This compact system was validated ex vivo on phantoms and in vivo by monitoring the blood flow on the forearm muscle of a healthy human subject. The measurements, performed at multiple source-detector separations and camera exposure times, demonstrate excellent agreement with the theory based on the correlation-diffusion model. In vivo data demonstrate the capability of tracking pulsatile blood flow with a high signal-to-noise ratio (>4 harmonics of the cardiac pulse frequency detected) and sensitivity to small changes in muscle blood flow. This micro-objective array-based design overcomes a key challenge towards wearable SCOS/SCOT devices.
dc.description.abstract
Peer Reviewed
dc.format
application/pdf
dc.relation
https://opg.optica.org/boe/fulltext.cfm?uri=boe-16-10-4091
dc.relation
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dc.relation
info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2021-2023/PID2023-151973OB-I00/ES/PLATAFORMA FOTONICA PORTATIL PARA LA DETECCION PRECOZ DEL SHOCK EN EL AMBITO PREHOSPITALARIO Y HOSPITALARIO/
dc.relation
info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2021-2023/PID2023-147553OB-I00/ES/NEUROMONITORES FOTONICOS PORTATILES NOVEDOSOS, PARA ENTORNOS REALISTAS/
dc.relation
LUX4MED/MEDLUX
dc.relation
info:eu-repo/grantAgreement/EC/H2020/786350/EU/Photometabolic Self-Replication/PSR
dc.relation
2019-FIB-00968
dc.relation
2022-SGR-01457
dc.relation
RIS3CAT-001-P-001682
dc.subject
Àrees temàtiques de la UPC::Física
dc.subject
Spectrum analysis
dc.subject
Anàlisi espectral
dc.title
On-skin, micro-objective enabled camera module for speckle contrast optical spectroscopy/tomography
