Título:
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Water-soluble aryl-extended calix[4]pyrroles with unperturbed aromatic cavities: synthesis and binding studies
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Autor/a:
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Hernandez-Alonso, Daniel; Zankowski, Stanislaw; Adriaenssens, Louis; Ballester, Pau
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Abstract:
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We report the synthesis of a novel, water-soluble aryl-extended calix[4]pyrrole receptor. The water-solubilising groups are placed at the lower rim of the receptor, leaving the binding pocket unperturbed and open for modification. Binding studies were performed with a series of pyridine N-oxides. These studies revealed the ability of the receptor to bind neutral and charged N-oxides in basified water with stability constants higher than 10(4) M-1. |
Fecha de creación:
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2014 |
Materia(s):
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pyridine n-oxides molecular recognition anion receptors lectins calixpyrroles capsules solvent |
Derechos:
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© The Royal Society of Chemistry |
Tipo de documento:
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Artículo |
DOI:
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https://dx.doi.org/10.1039/C4ob02108h
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Editor:
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ROYAL SOC CHEMISTRY
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Publish at:
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Organic & Biomolecular Chemistry
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Compartir:
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