Ni-Catalyzed Carboxylation of Unactivated Alkyl Chlorides with CO2
Author:
Börjesson, Marino; Moragas, Antoni; Martin, Ruben
Abstract:
A catalytic carboxylation of unactivated primary, secondary & tertiary alkyl chlorides with CO2 at atmospheric pressure is described. This protocol represents the first intermolecular cross-electrophile coupling of unactivated alkyl chlorides, thus leading to new knowledge in the cross-coupling arena.