Título:
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Reproducibility of optical coherence tomography airway imaging
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Autor/a:
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Kirby, Miranda; Ohtani, Keishi; Nickens, Taylor; Lopez Lisbona, Rosa Maria; Lee, Anthony M. D.; Shaipanich, Tawimas; Lane, Pierre; Macaulay, Calum; Lam, Stephen; Coxson, Harvey O.
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Abstract:
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Optical coherence tomography (OCT) is a promising imaging technique to evaluate small airway remodeling. However, the short-term insertion-reinsertion reproducibility of OCT for evaluating the same bronchial pathway has yet to be established. We evaluated 74 OCT data sets from 38 current or former smokers twice within a single imaging session. Although the overall insertion-reinsertion airway wall thickness (WT) measurement coefficient of variation (CV) was moderate at 12%, much of the variability between repeat imaging was attributed to the observer; CV for repeated measurements of the same airway (intra-observer CV) was 9%. Therefore, reproducibility may be improved by introduction of automated analysis approaches suggesting that OCT has potential to be an in-vivo method for evaluating airway remodeling in future longitudinal and intervention studies. (C) 2015 Optical Society of America |
Materia(s):
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-Òptica fisiològica -Biotecnologia -Physiological optics -Biotechnology |
Derechos:
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(c) Optical Society, 2015
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Tipo de documento:
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Artículo Artículo - Versión publicada |
Editor:
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OSA Publishing
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Compartir:
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