Título:
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The Role Of Omega-3 Polyunsaturated Fatty Acids In The Treatment Of Patients With Acute Respiratory Distress Syndrome: A Clinical Review
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Autor/a:
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García de Acilu, M.; Leal, S.; Caralt, B.; Roca, O.; Sabater Riera, Joan; Masclans, J. R.
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Abstract:
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Acute respiratory distress syndrome (ARDS) is defined as the acute onset of noncardiogenic edema and subsequent gas-exchange impairment due to a severe inflammatory process. Recent report on the prognostic value of eicosanoids in patients with ARDS suggests that modulating the inflammatory response through the use of polyunsaturated fatty acids may be a useful strategy for ARDS treatment. The use of enteral diets enriched with eicosapentaenoic acid (EPA) and gamma-linolenic acid (GLA) has reported promising results, showing an improvement in respiratory variables and haemodynamics. However, the interpretation of the studies is limited by their heterogeneity and methodology and the effect of omega-3 fatty acid-enriched lipid emulsion or enteral diets on patients with ARDS remains unclear. Therefore, the routine use of omega-3 fatty acid-enriched nutrition cannot be recommended and further large, homogeneous, and high-quality clinical trials need to be conducted to clarify the effectiveness of omega-3 polyunsaturated fatty acids. |
Materia(s):
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-Malalties de l'aparell respiratori -Malalties de l'aparell respiratori |
Derechos:
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cc by (c) García de Acilu et al., 2015
http://creativecommons.org/licenses/by/3.0/es/ |
Tipo de documento:
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Artículo Artículo - Versión publicada |
Editor:
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Hindawi Publishing Corporation
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