Título:
|
Mice with Pulmonary Tuberculosis Treated with Mycobacterium vaccae
Develop Strikingly Enhanced Recall Gamma Interferon Responses
to M. vaccae Cell Wall Skeleton
|
Autor/a:
|
Rodríguez Güell, Elisabeth; Agustí, Gemma; Corominas Sánchez, Mercè; Cardona, Pere Joan; Luquin, Marina; Julián, Esther
|
Abstract:
|
Whole heat-killed Mycobacterium vaccae is used as an immunotherapeutic agent in tuberculosis (TB), but the compound(s) that triggers its immunostimulatory ability is not known. Here, we show that among different subcellular fractions, the cell wall skeleton induced a prominent expression of gamma interferon in splenocytes from both non-TB and TB M. vaccae-treated mice. |
Materia(s):
|
-Mycobacterium tuberculosis -Ratolins (Animals de laboratori) -Mice (Laboratory animals) |
Derechos:
|
(c) American Society for Microbiology, 2008
|
Tipo de documento:
|
Artículo Artículo - Versión publicada |
Editor:
|
American Society for Microbiology
|
Compartir:
|
|