Título:
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Immune Exclusion-Wnt/CTNNB1 Class Predicts Resistance to Immunotherapies in HCC
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Autor/a:
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Pinyol, Roser; Sia, Daniela; Llovet i Bayer, Josep Maria
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Notas:
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Next-generation sequencing has provided information on actionable targets and biomarkers of response in oncology. In hepatocellular carcinoma (HCC), Wnt/CTNNB1 mutations characterize the immune-excluded class (cold tumors) and might represent the biomarkers predicting resistance to immune checkpoint inhibitors. Large-scale validation of these data is needed to customize immunotherapy in advanced HCC.See related article by Harding et al.©2019 American Association for Cancer Research. |
Materia(s):
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-Marcadors bioquímics -Càncer de fetge -Biochemical markers -Liver cancer |
Derechos:
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(c) American Association for Cancer Research, 2019
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Tipo de documento:
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Artículo Artículo - Versión aceptada |
Editor:
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American Association for Cancer Research
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Compartir:
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