2(1H)-Pyrazinones from acyclic building blocks: methods of synthesis and further derivatizations

dc.contributor.author
Riesco-Llach, Gerard
dc.contributor.author
Planas i Grabuleda, Marta
dc.contributor.author
Feliu Soley, Lidia
dc.contributor.author
Joule, John A.
dc.date.issued
2023-01-04
dc.identifier
http://hdl.handle.net/10256/22462
dc.description.abstract
Pyrazinones (2(1H)-pyrazinones) are found as components of a range of natural substances and are involved in the preparation of a great number of bioactive molecules. Synthesis of such compounds, and analogues, requires knowledge of the heterocyclic properties of pyrazinones and, in particular, methods for their ring construction. This review deals with the strategies that have been developed for the synthesis of pyrazinones from acyclic precursors, especially α-amino acid-derived units, from the first examples in 1905 up to the most recent in 2021
dc.description.abstract
G. R.-L. is recipient of a predoctoral fellowship from the University of Girona (IFUdG2020)
dc.format
application/pdf
dc.language
eng
dc.publisher
Royal Society of Chemistry (RSC)
dc.relation
info:eu-repo/semantics/altIdentifier/doi/10.1039/D2RA07227K
dc.relation
info:eu-repo/semantics/altIdentifier/eissn/2046-2069
dc.rights
Attribution-NonCommercial 4.0 International
dc.rights
http://creativecommons.org/licenses/by-nc/4.0/
dc.rights
info:eu-repo/semantics/openAccess
dc.source
RSC Advances, 2023,vol. 13, p. 1162-1184
dc.source
Articles publicats (D-Q)
dc.subject
Compostos bioactius -- Síntesi
dc.subject
Bioactive compounds -- Synthesis
dc.subject
Pirazines -- Síntesi
dc.subject
Pyrazines -- Synthesis
dc.title
2(1H)-Pyrazinones from acyclic building blocks: methods of synthesis and further derivatizations
dc.type
info:eu-repo/semantics/article
dc.type
info:eu-repo/semantics/publishedVersion
dc.type
peer-reviewed


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