Sistema de Salut de Catalunya
Institut Català de la Salut
[Serrano C] Sarcoma Translational Research Group, Vall d’Hebron Institute of Oncology (VHIO), Barcelona, Spain. Vall d’Hebron Hospital Universitari, Barcelona, Spain. [Álvarez R] Hospital General Universitario Gregorio Marañón, Madrid, Spain. [Carrasco JA] Hospital Álvaro Cunqueiro–Complejo Hospitalario Universitario de Vigo, Pontevedra, Spain. [Marquina G] Hospital Universitario Clínico San Carlos, Madrid, Spain. [Martínez-García J] Hospital Universitario Virgen de la Arrixaca, Murcia, Spain. [Martínez-Marín V] Hospital Universitario la Paz, Madrid, Spain
Vall d'Hebron Barcelona Hospital Campus
2023-09-05T12:07:25Z
2023-09-05T12:07:25Z
2023-09
Avapritinib; Imatinib; Ripretinib
Avapritinib; Imatinib; Ripretinib
Avapritinib; Imatinib; Ripretinib
Gastrointestinal stromal tumor (GIST) is the most common malignant neoplasm of mesenchymal origin, and a paradigmatic model for a successful rational development of targeted therapies in cancer. The introduction of tyrosine kinase inhibitors with activity against KIT/PDGFRA in both localized and advanced stages has remarkably improved the survival in a disease formerly deemed resistant to all systemic therapies. These guidelines are elaborated by the conjoint effort of the Spanish Society of Medical Oncology (SEOM) and the Spanish Sarcoma Research Group (GEIS) and provide a multidisciplinary and updated consensus for the diagnosis and treatment of GIST patients. We strongly encourage that the managing of these patients should be performed within multidisciplinary teams in reference centers.
Article
Published version
English
Decisió de grup; Tracte gastrointestinal - Càncer - Tractament; Tracte gastrointestinal - Càncer - Diagnòstic; DISEASES::Digestive System Diseases::Digestive System Neoplasms::Gastrointestinal Neoplasms::Digestive System Diseases::Gastrointestinal Stromal Tumors; PUBLIC HEALTH::Health Care (Public Health)::Delivery of Health Care::Disease Management; PSYCHIATRY AND PSYCHOLOGY::Behavior and Behavior Mechanisms::Psychology, Social::Group Processes::Consensus; ENFERMEDADES::enfermedades del sistema digestivo::neoplasias del sistema digestivo::neoplasias gastrointestinales::enfermedades del sistema digestivo::tumores del estroma gastrointestinal; SALUD PÚBLICA::atención a la salud (salud pública)::prestación sanitaria::tratamiento de las enfermedades; PSIQUIATRÍA Y PSICOLOGÍA::conducta y mecanismos de la conducta::psicología social::procesos de grupo::consenso
Springer
Clinical and Translational Oncology;25
https://doi.org/10.1007/s12094-023-03177-7
Attribution 4.0 International
http://creativecommons.org/licenses/by/4.0/
Articles científics - HVH [3436]
