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Patient-Centric Approaches for Phase I Combination Trials Come on Stage

To access the full text documents, please follow this link: https://hdl.handle.net/11351/10254

Author

Hernando-Calvo, Alberto

GARRALDA, Elena

Other authors

Institut Català de la Salut

Vall d’Hebron Hospital Universitari, Barcelona, Spain. Vall d’Hebron Institute of Oncology (VHIO), Barcelona, Spain

Vall d'Hebron Barcelona Hospital Campus

Publication date

2023-09-07T12:10:04Z

2023-09-07T12:10:04Z

2023-08-04



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Abstract

Combination trials; Cancer

Assajos combinats; Càncer

Ensayos combinados; Cáncer

A disruptive clinical trial design allowed Drilon and colleagues to demonstrate proof of concept of the potential of PF-07284892 to overcome resistance mechanisms to targeted therapies in the clinic.

The authors would like to thank the CaixaResearch Advanced Oncology Research Program supported by Fundació La Caixa (LCF/PR/CE07/50610001).

Document Type

Article

Published version

Language

English

Subjects and keywords

Càncer - Tractament; Oncogens; Atenció centrada en el pacient; DISEASES::Neoplasms; Other subheadings::Other subheadings::Other subheadings::/drug therapy; PHENOMENA AND PROCESSES::Genetic Phenomena::Genetic Structures::Genome::Genome Components::Genes::Genes, Neoplasm::Oncogenes; HEALTH CARE::Health Services Administration::Patient Care Management::Comprehensive Health Care::Primary Health Care::Patient-Centered Care; ENFERMEDADES::neoplasias; Otros calificadores::Otros calificadores::Otros calificadores::/farmacoterapia; FENÓMENOS Y PROCESOS::fenómenos genéticos::estructuras genéticas::genoma::componentes genómicos::genes::genes de neoplasias::oncogenes; ATENCIÓN DE SALUD::administración de los servicios de salud::gestión de la atención al paciente::atención integral de salud::atención primaria de la salud::atención centrada en el paciente

Publisher

American Association for Cancer Research

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Cancer Discovery;13(8)

https://doi.org/10.1158/2159-8290.CD-23-0534

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Rights

Attribution 4.0 International

http://creativecommons.org/licenses/by/4.0/

This item appears in the following Collection(s)

Articles científics - HVH [3439]