The Role of Molecular Allergens in the Diagnosis of Cat-Pork Syndrome: An Unusual Case Report

O Papel dos Alergénios Moleculares no Diagnóstico de Síndrome Gato-Porco: A Propósito de um Caso Clínico Raro

Other authors

Institut Català de la Salut

[Barradas Lopes J] Department of Immunoallergology, Centro Hospitalar de Vila Nova de Gaia/Espinho, Vila Nova de Gaia, Portugal. [Labrador-Horrilo M] Servei d’Al·lergologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Universitat Autònoma de Barcelona, Bellatera, Spain. [Bartolomé B] Research and Development Department of Roxall, Bilbao, Spain. [Cunha L] Department of Immunoallergology, Centro Hospital Universitário do Porto, Porto, Portugal

Vall d'Hebron Barcelona Hospital Campus

Publication date

2023-01-26T10:19:14Z

2023-01-26T10:19:14Z

2022-05



Abstract

Cats; Food Hypersensitivity; Swine


Gats; Hipersensibilitat alimentària; Porcs


Gatos; Hipersensibilidad alimentaria; Puercos


Cat-pork syndrome is a rare condition, with few cases reported in the literature. This syndrome is justified by the homology between serum albumins from cat and pork. Evidence suggests that a primary sensitization to cat serum albumin Fel d 2 occurs, followed by allergic reactions after ingestion of pork meat containing serum albumin Sus s 1. Due to homology between other mammalian serum albumins, reactions with other meats can also be present. We report a well-documented case report of a patient with cat-pork syndrome, with initial mild and non-specific manifestations to well-cooked pork that were overlooked. Component resolved diagnosis was essential to establish the diagnosis, which confirmed the involvement of Fed 2 and Sus s 1, but less relevant in helping to define avoidance diets, since the sensitization profile was not in accordance with clinical manifestations.

Document Type

Article


Published version

Language

English

Publisher

Ordem dos Médicos

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Rights

Attribution-NonCommercial 4.0 International

http://creativecommons.org/licenses/by-nc/4.0/

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