Título:
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Critical Behavior and Axis Defining Symmetry Breaking in Hydra Embryonic Development
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Autor/a:
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Gamba, Andrea; Nicodemi, Mario; Soriano i Fradera, Jordi; Ott, Albrecht
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Otros autores:
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Universitat de Barcelona |
Abstract:
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The formation of a hollow cellular sphere is often one of the first steps of multicellular embryonic development. In the case of Hydra, the sphere breaks its initial symmetry to form a foot-head axis. During this process a gene, ks1, is increasingly expressed in localized cell domains whose size distribution becomes scale-free at the axis-locking moment. We show that a physical model based solely on the production and exchange of ks1-promoting factors among neighboring cells robustly reproduces the scaling behavior as well as the experimentally observed spontaneous and temperature-directed symmetry breaking. |
Materia(s):
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-Hidrozous -Biofísica -Embriologia -Regeneració (Biologia) -Cèl·lules -Càncer -Hydrozoa -Biophysics -Embryology -Regeneration (Biology) -Cells -Cancer |
Derechos:
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(c) American Physical Society, 2012
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Tipo de documento:
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Artículo Artículo - Versión publicada |
Editor:
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American Physical Society
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Compartir:
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