Organocatalytic N-formylation of amines by CO2 in batch and continuous flow 

Zanda, Nicola; Primitivo, Ludovica; Chaudari, Moreshwar; Kleij, Arjan W.; Pericàs, Miquel A. (2022-11-21)

A continuous flow organocatalytic synthesis of formamides has been developed using amines and CO2 reaction partners in the presence of a silane reductant. The process is conducted under comparatively mild reaction conditions ...