N-Iodosuccinimide promoted Hofmann-Löffler Reactions of Sulfonimides under Visible Light

Abstract

<p> Conditions for an attractive and productive protocol for the position-selective intramolecular C-H amination of aliphatic groups (Hofmann-L&ouml;ffler reaction) are reported employing sulfonimides as nitrogen sources. <em>N</em>-Iodosuccinimide is the only required promoter for this transformation, which is conveniently initiated by visible light. The overall transformation provides pyrrolidines under mild and selective conditions as demonstrated for 17 different substrates.</p>