Ni-catalyzed Carboxylation of Unactivated Primary Alkyl Bromides and Sulfonates with CO2

Abstract

<p> &nbsp;</p> <p style="margin: 0.0px 0.0px 0.0px 0.0px; font: 10.5px 'Times New Roman'"> A Ni-catalyzed carboxylation of <i>unactivated</i></p> <p style="margin: 0.0px 0.0px 0.0px 0.0px; font: 10.5px 'Times New Roman'"> primary alkyl bromides and sulfonates with CO<span style="font: 7.0px 'Times New Roman'">2 </span>at</p> <p style="margin: 0.0px 0.0px 0.0px 0.0px; font: 10.5px 'Times New Roman'"> atmospheric pressure is described. The method is characterized</p> <p style="margin: 0.0px 0.0px 0.0px 0.0px; font: 10.5px 'Times New Roman'"> by its mild conditions and a remarkable wide</p> <p style="margin: 0.0px 0.0px 0.0px 0.0px; font: 10.5px 'Times New Roman'"> scope without the need for air- or moisture-sensitive</p> <p style="margin: 0.0px 0.0px 0.0px 0.0px; font: 10.5px 'Times New Roman'"> reagents, thus becoming a user-friendly and operationally</p> <p style="margin: 0.0px 0.0px 0.0px 0.0px; font: 10.5px 'Times New Roman'"> simple protocol en route to carboxylic acids.</p>