Ni-catalyzed Regioselective Hydrocarboxylation of Alkynes with CO2 by Using Simple Alcohols as Proton Sources

Abstract

<p> &nbsp;</p> <p style="margin: 0.0px 0.0px 0.0px 0.0px; font: 10.5px 'Times New Roman'"> A mild and user-friendly Ni-catalyzed regioselective</p> <p style="margin: 0.0px 0.0px 0.0px 0.0px; font: 10.5px 'Times New Roman'"> hydrocarboxylation of alkynes with CO<span style="font: 7.0px 'Times New Roman'">2 </span>(1</p> <p style="margin: 0.0px 0.0px 0.0px 0.0px; font: 10.5px 'Times New Roman'"> bar) is described. This protocol is characterized by a</p> <p style="margin: 0.0px 0.0px 0.0px 0.0px; font: 10.5px 'Times New Roman'"> wide scope while obviating the need for sensitive organometallic</p> <p style="margin: 0.0px 0.0px 0.0px 0.0px; font: 10.5px 'Times New Roman'"> species and by an unprecedented regioselectivity</p> <p style="margin: 0.0px 0.0px 0.0px 0.0px; font: 10.5px 'Times New Roman'"> pattern using simple alcohols as proton sources.</p>