A chemically-bound glutathione sensor bioinspired by the defense of organisms against heavy metal contamination: Optimization of the immobilization conditions

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Title:	A chemically-bound glutathione sensor bioinspired by the defense of organisms against heavy metal contamination: Optimization of the immobilization conditions
Author:	Pérez-Ràfols, Clara; Serrano i Plana, Núria; Díaz Cruz, José Manuel; Ariño Blasco, Cristina; Esteban i Cortada, Miquel
Other authors:	Universitat de Barcelona
Abstract:	The influence of the experimental conditions (glutathione concentration and incubation time and temperature) concerning the covalent immobilization of glutathione via carbodiimide coupling on the behavior of a glutathione modified screen-printed carbon electrode obtained by electrografting is evaluated. The optimized parameters fasten the modification process and improve the performance of the sensor as compared to the usual procedure. This suggests the convenience of a tailored preparation of metal sensors based on metal-binding biomolecules such as glutathione.
Subject(s):	-Glutatió -Metalls pesants -Voltametria -Glutathione -Heavy metals -Voltammetry
Rights:	cc-by (c) Pérez-Ràfols, Clara et al., 2017 http://creativecommons.org/licenses/by/3.0/es
Document type:	Article Article - Published version
Published by:	MDPI
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