Desymmetrisation of meso-diones promoted by a highly recyclable polymersupported chiral phosphoric acid catalyst

Publication date

2018-02-12



Abstract

A polystyrene-supported BINOL-derived chiral phosphoric acid has been applied to the desymmetrisation of meso-diones to produce enantioenriched cyclohexenones. The catalytic resin has proven highly active and robust, giving rise to Hajos–Parrish or Wieland–Miescher type products in good yields and enantioselectivities, while allowing for extended recycling.

Document Type

Article


Accepted version

Language

English

Pages

6910 p.

Grant Agreement Number

CTQ2015-69136-R

Grant 2014SGR827

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Documents

2018 Desymmetrisation of meso-diones.pdf

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Rights

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