A continuous phenotype space model of cancer evolution

dc.contributor.author
Masip, D.
dc.contributor.author
Korobeinikiov, A.
dc.date.accessioned
2020-10-13T12:20:11Z
dc.date.accessioned
2024-09-19T13:16:24Z
dc.date.available
2020-10-13T12:20:11Z
dc.date.available
2024-09-19T13:16:24Z
dc.date.issued
2017-01-01
dc.identifier.uri
http://hdl.handle.net/2072/377515
dc.description.abstract
It was suggested that the ability of cancer to avoid immune response pressure (that should be expected to be capable to annihilate cancer at its early stage) can be attributed to the ability of the cancer cells to evolve. The goal of this notice is to illustrate this possibility by the means of mathematical modelling. In this notice, we construct a simple mechanistic model of cancer evolution, which is based upon a classical model of cancer-immune response interaction. Numerical simulations confirm the hypothesis that if cancer mutates fast enough and if immune response is not sufficiently strong, then cancer is able to avoid immune response pressure by evolution.
eng
dc.format.extent
13 p.
cat
dc.language.iso
eng
cat
dc.rights
L'accés als continguts d'aquest document queda condicionat a l'acceptació de les condicions d'ús establertes per la següent llicència Creative Commons:http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.source
RECERCAT (Dipòsit de la Recerca de Catalunya)
dc.subject.other
Matemàtiques
cat
dc.title
A continuous phenotype space model of cancer evolution
cat
dc.type
info:eu-repo/semantics/preprint
cat
dc.subject.udc
51
cat
dc.embargo.terms
cap
cat
dc.rights.accessLevel
info:eu-repo/semantics/openAccess


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